eF-site ID 5mur-C PDB Code 5mur Chain C click to enlarge Title X-ray structure of the F14'A mutant of GLIC in complex with propofol Classification TRANSPORT PROTEIN Compound Proton-gated ion channel Source (GLIC_GLOVI) Sequence C:  VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLS LSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENA RDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIES FTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILP MLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVET NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQ PARAASITRASRIAFPVVFLLANIILAFLFF Description Functional site 1) chain C residue 77 type sequence R description binding site for residue ACT B 405 source : AD1 2) chain C residue 131 type sequence I description binding site for residue ACT B 405 source : AD1 3) chain C residue 181 type sequence E description binding site for residue ACT B 405 source : AD1 4) chain C residue 73 type sequence I description binding site for residue ACT C 401 source : AD3 5) chain C residue 74 type sequence P description binding site for residue ACT C 401 source : AD3 6) chain C residue 76 type sequence I description binding site for residue ACT C 401 source : AD3 7) chain C residue 85 type sequence R description binding site for residue ACT C 401 source : AD3 8) chain C residue 102 type sequence Y description binding site for residue ACT C 401 source : AD3 9) chain C residue 78 type sequence F description binding site for residue CL C 402 source : AD4 10) chain C residue 68 type sequence P description binding site for residue NA C 403 source : AD5 11) chain C residue 71 type sequence I description binding site for residue NA C 403 source : AD5 12) chain C residue 118 type sequence R description binding site for residue PLC C 404 source : AD6 13) chain C residue 121 type sequence F description binding site for residue PLC C 404 source : AD6 14) chain C residue 194 type sequence Y description binding site for residue PLC C 404 source : AD6 15) chain C residue 254 type sequence Y description binding site for residue PLC C 404 source : AD6 16) chain C residue 307 type sequence N description binding site for residue PLC C 404 source : AD6 17) chain C residue 42 type sequence F description binding site for residue ACT C 405 source : AD7 18) chain C residue 105 type sequence R description binding site for residue ACT C 405 source : AD7 19) chain C residue 245-252 type TOPO_DOM sequence NLPKTPYM description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 20) chain C residue 220-244 type TRANSMEM sequence SYEANVTLVVSTLIAHIAANILVET description Helical source Swiss-Prot : SWS_FT_FI2 21) chain C residue 253-281 type TRANSMEM sequence TYTGAIIFMIYLFYFVAVIEVTVQHYLKV description Helical source Swiss-Prot : SWS_FT_FI2 22) chain C residue 194-216 type TRANSMEM sequence YFSYIPNIILPMLFILFISWTAF description Helical source Swiss-Prot : SWS_FT_FI2 23) chain C residue 217-219 type TOPO_DOM sequence WST description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 24) chain C residue 282-284 type TOPO_DOM sequence ESQ description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3

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