eF-site ID 5mur-B PDB Code 5mur Chain B click to enlarge Title X-ray structure of the F14'A mutant of GLIC in complex with propofol Classification TRANSPORT PROTEIN Compound Proton-gated ion channel Source (GLIC_GLOVI) Sequence B:  VSPPPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLS LSWKDRRLAFDPVRSGVRVKTYEPEAIWIPEIRFVNVENA RDADVVDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIES FTAVVKPANFALEDRLESKLDYQLRISRQYFSYIPNIILP MLFILFISWTAFWSTSYEANVTLVVSTLIAHIAANILVET NLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQ PARAASITRASRIAFPVVFLLANIILAFLFF Description Functional site 1) chain B residue 77 type sequence R description binding site for residue ACT A 405 source : AC5 2) chain B residue 131 type sequence I description binding site for residue ACT A 405 source : AC5 3) chain B residue 181 type sequence E description binding site for residue ACT A 405 source : AC5 4) chain B residue 74 type sequence P description binding site for residue ACT B 401 source : AC6 5) chain B residue 76 type sequence I description binding site for residue ACT B 401 source : AC6 6) chain B residue 85 type sequence R description binding site for residue ACT B 401 source : AC6 7) chain B residue 102 type sequence Y description binding site for residue ACT B 401 source : AC6 8) chain B residue 78 type sequence F description binding site for residue CL B 402 source : AC7 9) chain B residue 68 type sequence P description binding site for residue NA B 403 source : AC8 10) chain B residue 71 type sequence I description binding site for residue NA B 403 source : AC8 11) chain B residue 73 type sequence I description binding site for residue NA B 403 source : AC8 12) chain B residue 118 type sequence R description binding site for residue PLC B 404 source : AC9 13) chain B residue 121 type sequence F description binding site for residue PLC B 404 source : AC9 14) chain B residue 194 type sequence Y description binding site for residue PLC B 404 source : AC9 15) chain B residue 254 type sequence Y description binding site for residue PLC B 404 source : AC9 16) chain B residue 307 type sequence N description binding site for residue PLC B 404 source : AC9 17) chain B residue 42 type sequence F description binding site for residue ACT B 405 source : AD1 18) chain B residue 105 type sequence R description binding site for residue ACT B 405 source : AD1 19) chain B residue 119 type sequence Y description binding site for residue PFL B 407 source : AD2 20) chain B residue 120 type sequence P description binding site for residue PFL B 407 source : AD2 21) chain B residue 197 type sequence Y description binding site for residue PFL B 407 source : AD2 22) chain B residue 201 type sequence I description binding site for residue PFL B 407 source : AD2 23) chain B residue 202 type sequence I description binding site for residue PFL B 407 source : AD2 24) chain B residue 205 type sequence M description binding site for residue PFL B 407 source : AD2 25) chain B residue 255 type sequence T description binding site for residue PFL B 407 source : AD2 26) chain B residue 258 type sequence I description binding site for residue PFL B 407 source : AD2 27) chain B residue 245-252 type TOPO_DOM sequence NLPKTPYM description Periplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 28) chain B residue 194-216 type TRANSMEM sequence YFSYIPNIILPMLFILFISWTAF description Helical source Swiss-Prot : SWS_FT_FI2 29) chain B residue 220-244 type TRANSMEM sequence SYEANVTLVVSTLIAHIAANILVET description Helical source Swiss-Prot : SWS_FT_FI2 30) chain B residue 253-281 type TRANSMEM sequence TYTGAIIFMIYLFYFVAVIEVTVQHYLKV description Helical source Swiss-Prot : SWS_FT_FI2 31) chain B residue 217-219 type TOPO_DOM sequence WST description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3 32) chain B residue 282-284 type TOPO_DOM sequence ESQ description Cytoplasmic => ECO:0000255 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links