eF-site ID 5mpn-A PDB Code 5mpn Chain A click to enlarge Title Crystal structure of CREBBP bromodomain complexed with FA26 Classification TRANSCRIPTION Compound CREB-binding protein Source (CBP_HUMAN) Sequence A:  SMRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ LLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVW LMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSL Description (1)  CREB-binding protein (E.C.2.3.1.48) Functional site 1) chain A residue 1109 type sequence L description binding site for residue YE5 A 1201 source : AC1 2) chain A residue 1110 type sequence P description binding site for residue YE5 A 1201 source : AC1 3) chain A residue 1115 type sequence V description binding site for residue YE5 A 1201 source : AC1 4) chain A residue 1130 type sequence K description binding site for residue YE5 A 1201 source : AC1 5) chain A residue 1131 type sequence N description binding site for residue YE5 A 1201 source : AC1 6) chain A residue 1168 type sequence N description binding site for residue YE5 A 1201 source : AC1 7) chain A residue 1173 type sequence R description binding site for residue YE5 A 1201 source : AC1 8) chain A residue 1079 type sequence S description binding site for residue YE5 A 1202 source : AC2 9) chain A residue 1099 type sequence E description binding site for residue YE5 A 1202 source : AC2 10) chain A residue 1102 type sequence Y description binding site for residue YE5 A 1202 source : AC2 11) chain A residue 1103 type sequence R description binding site for residue YE5 A 1202 source : AC2 12) chain A residue 1112 type sequence R description binding site for residue YE5 A 1202 source : AC2 13) chain A residue 1151 type sequence W description binding site for residue YE5 A 1202 source : AC2 14) chain A residue 1079 type sequence S description binding site for residue EDO A 1203 source : AC3 15) chain A residue 1080 type sequence M description binding site for residue EDO A 1203 source : AC3 16) chain A residue 1120 type sequence L description binding site for residue EDO A 1203 source : AC3 17) chain A residue 1131 type sequence N description binding site for residue EDO A 1203 source : AC3 18) chain A residue 1087 type sequence P description binding site for residue EDO A 1204 source : AC4 19) chain A residue 1088 type sequence E description binding site for residue EDO A 1204 source : AC4 20) chain A residue 1165 type sequence W description binding site for residue EDO A 1204 source : AC4 21) chain A residue 1175 type sequence Y description binding site for residue EDO A 1204 source : AC4 22) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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