|
|
eF-site ID
|
5mpk-B |
|
PDB Code
|
5mpk |
|
Chain
|
B |
|
click to enlarge
|
|
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Title
|
Crystal structure of CREBBP bromodomain complexed with DK19 |
|
Classification
|
TRANSCRIPTION |
|
Compound
|
CREB-binding protein |
|
Source
|
(CBP_HUMAN) |
|
|
Sequence
|
B: |
IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP
DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN
AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQS
|
|
|
Description
|
(1) |
CREB-binding protein (E.C.2.3.1.48)
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
1110 |
| type |
|
| sequence |
P
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
2)
|
chain |
B |
| residue |
1115 |
| type |
|
| sequence |
V
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
3)
|
chain |
B |
| residue |
1120 |
| type |
|
| sequence |
L
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
4)
|
chain |
B |
| residue |
1168 |
| type |
|
| sequence |
N
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
5)
|
chain |
B |
| residue |
1173 |
| type |
|
| sequence |
R
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
6)
|
chain |
B |
| residue |
1174 |
| type |
|
| sequence |
V
|
| description |
binding site for residue 0BC B 1201
|
| source |
: AC2
|
|
|
|