eF-site ID 5mpk-AB PDB Code 5mpk Chain A, B click to enlarge Title Crystal structure of CREBBP bromodomain complexed with DK19 Classification TRANSCRIPTION Compound CREB-binding protein Source (CBP_HUMAN) Sequence A:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQS B:  IFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIP DYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNN AWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQS Description (1)  CREB-binding protein (E.C.2.3.1.48) Functional site 1) chain A residue 1109 type sequence L description binding site for residue 0BC A 1201 source : AC1 2) chain A residue 1110 type sequence P description binding site for residue 0BC A 1201 source : AC1 3) chain A residue 1113 type sequence Q description binding site for residue 0BC A 1201 source : AC1 4) chain A residue 1115 type sequence V description binding site for residue 0BC A 1201 source : AC1 5) chain A residue 1120 type sequence L description binding site for residue 0BC A 1201 source : AC1 6) chain A residue 1168 type sequence N description binding site for residue 0BC A 1201 source : AC1 7) chain A residue 1173 type sequence R description binding site for residue 0BC A 1201 source : AC1 8) chain A residue 1165 type sequence W description binding site for residue 0BC B 1201 source : AC2 9) chain B residue 1110 type sequence P description binding site for residue 0BC B 1201 source : AC2 10) chain B residue 1115 type sequence V description binding site for residue 0BC B 1201 source : AC2 11) chain B residue 1120 type sequence L description binding site for residue 0BC B 1201 source : AC2 12) chain B residue 1168 type sequence N description binding site for residue 0BC B 1201 source : AC2 13) chain B residue 1173 type sequence R description binding site for residue 0BC B 1201 source : AC2 14) chain B residue 1174 type sequence V description binding site for residue 0BC B 1201 source : AC2 15) chain A residue 1108-1167 type prosite sequence SLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQY QEPWQYVDDVWLMFNNAWLY description BROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY source prosite : PS00633

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