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eF-site ID
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5mpc-L |
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PDB Code
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5mpc |
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Chain
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L |
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click to enlarge
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Title
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26S proteasome in presence of BeFx (s4) |
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Classification
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HYDROLASE |
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Compound
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Proteasome subunit alpha type-1 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); |
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Sequence
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L: |
EQEAHNKALNQFKRKLLEHRRYDDQLKQRRQNIRDLEKLY
DKTENDIKALQSIGQLIGEVMKELSEEKYIVKASSGPRYI
VGVRNSVDRSKLKKGVRVTLDITTLTIMRILPRETDPLVY
NMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPEIFQ
RVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPA
SGIVDKYIGESARIIREMFAYAKEHEPCIIFMDEVDAIGG
RRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATN
RPDTLDPALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKV
KKTGEFDFEAAVKMSDGFNGADIRNCATEAGFFAIRDDRD
HINPDDLMKAVRKVAEVKKLEGTIEYQK
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Description
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(1) |
Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-6 (E.C.3.4.25.1), Probable proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), 26S protease regulatory subunit 7 homolog, 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6B homolog, 26S protease subunit RPT4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 8 homolog, Ubiquitin carboxyl-terminal hydrolase 6 (E.C.3.4.19.12), 26S proteasome regulatory subunit RPN10, Ubiquitin carboxyl-terminal hydrolase RPN11 (E.C.3.4.19.12), 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN13, 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit RPN9
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Functional site
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1)
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chain |
L |
| residue |
182 |
| type |
|
| sequence |
G
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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2)
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chain |
L |
| residue |
225 |
| type |
|
| sequence |
G
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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3)
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chain |
L |
| residue |
226 |
| type |
|
| sequence |
T
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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4)
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chain |
L |
| residue |
227 |
| type |
|
| sequence |
G
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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5)
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chain |
L |
| residue |
228 |
| type |
|
| sequence |
K
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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6)
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chain |
L |
| residue |
229 |
| type |
|
| sequence |
T
|
| description |
binding site for residue ADP L 501
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| source |
: AC7
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7)
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chain |
L |
| residue |
328 |
| type |
|
| sequence |
N
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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8)
|
chain |
L |
| residue |
389 |
| type |
|
| sequence |
A
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| description |
binding site for residue ADP L 501
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| source |
: AC7
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9)
|
chain |
L |
| residue |
229 |
| type |
|
| sequence |
T
|
| description |
binding site for residue MG L 502
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| source |
: AC8
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10)
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chain |
L |
| residue |
321-339 |
| type |
prosite |
| sequence |
TKIIMATNRPDTLDPALLR
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| description |
AAA AAA-protein family signature. IkIImATNrldiLDpALl.R
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| source |
prosite : PS00674
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