eF-site ID 5mpb-d
PDB Code 5mpb
Chain d

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Title 26S proteasome in presence of AMP-PNP (s3)
Classification HYDROLASE
Compound Proteasome subunit alpha type-1
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence d:  GYDRALSIFSPDGHIFQVEYALEAVKRGTCAVGVKGKNCV
VLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADS
RILIEKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQ
SGGVRPFGVSTLIAGFDPRDDEPKLYQTEPSGIYSSWSAQ
TIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEV
VQTGAKNIEITVVKPDSDIVALSSEEINQYVTQIEQEKQE
Description (1)  Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-6 (E.C.3.4.25.1), Probable proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), 26S protease regulatory subunit 7 homolog, 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6B homolog, 26S protease subunit RPT4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 8 homolog, 26S proteasome regulatory subunit RPN10, Ubiquitin carboxyl-terminal hydrolase RPN11 (E.C.3.4.19.12), 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN13, 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit RPN9


Functional site

1) chain d
residue 2-24
type prosite
sequence YDRALSIFSPDGHIFQVEYALEA
description PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsnSvFSPdGRnfQVEYAvkA
source prosite : PS00388

2) chain d
residue 32-79
type prosite
sequence VGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVL
SFSGLNAD
description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
source prosite : PS00854


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