eF-site ID 5mpb-I
PDB Code 5mpb
Chain I

click to enlarge
Title 26S proteasome in presence of AMP-PNP (s3)
Classification HYDROLASE
Compound Proteasome subunit alpha type-1
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence I:  TRCKLKLLRMERIKDHLLLEEEFVSNSEILKPFEKKQEEE
KKQLEEIRGNPLSIGTLEEIIDDDHAIVTSPTMPDYYVSI
LSFVDKELLEPGCSVLLHHKTMSIVGVLQDDADPMVSVMK
MDKSPTESYSDIGGLESQIQEIKESVELPLTHPELYEEMG
IKPPKGVILYGAPGTGKTLLAKAVANQTSATFLRIVGSEL
IQKYLGDGPRLCRQIFKVAGENAPSIVFIDEIDAIGTKRY
DSNSGGEREIQRTMLELLNQLDGFDDRGDVKVIMATNKIE
TLDPALIRPGRIDRKILFENPDLSTKKKILGIHTSKMNLS
EDVNLETLVTTKDDLSGADIQAMCTEAGLLALRERRMQVT
AEDFKQAKERVMKNKVEENLEGLYL
Description (1)  Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-6 (E.C.3.4.25.1), Probable proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), 26S protease regulatory subunit 7 homolog, 26S protease regulatory subunit 4 homolog, 26S protease regulatory subunit 6B homolog, 26S protease subunit RPT4, 26S protease regulatory subunit 6A, 26S protease regulatory subunit 8 homolog, 26S proteasome regulatory subunit RPN10, Ubiquitin carboxyl-terminal hydrolase RPN11 (E.C.3.4.19.12), 26S proteasome regulatory subunit RPN12, 26S proteasome regulatory subunit RPN13, 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit RPN8, 26S proteasome regulatory subunit RPN9


Functional site

1) chain I
residue 184
type
sequence I
description binding site for residue ANP I 501
source : AC3

2) chain I
residue 186
type
sequence G
description binding site for residue ANP I 501
source : AC3

3) chain I
residue 187
type
sequence L
description binding site for residue ANP I 501
source : AC3

4) chain I
residue 225
type
sequence P
description binding site for residue ANP I 501
source : AC3

5) chain I
residue 226
type
sequence G
description binding site for residue ANP I 501
source : AC3

6) chain I
residue 227
type
sequence T
description binding site for residue ANP I 501
source : AC3

7) chain I
residue 228
type
sequence G
description binding site for residue ANP I 501
source : AC3

8) chain I
residue 229
type
sequence K
description binding site for residue ANP I 501
source : AC3

9) chain I
residue 230
type
sequence T
description binding site for residue ANP I 501
source : AC3

10) chain I
residue 361
type
sequence I
description binding site for residue ANP I 501
source : AC3

11) chain I
residue 389
type
sequence G
description binding site for residue ANP I 501
source : AC3

12) chain I
residue 393
type
sequence Q
description binding site for residue ANP I 501
source : AC3

13) chain I
residue 230
type
sequence T
description binding site for residue MG I 502
source : AC4

14) chain I
residue 322-340
type prosite
sequence VKVIMATNKIETLDPALIR
description AAA AAA-protein family signature. IkIImATNrldiLDpALl.R
source prosite : PS00674

15) chain I
residue 255
type MOD_RES
sequence K
description Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
source Swiss-Prot : SWS_FT_FI3

16) chain I
residue 290
type MOD_RES
sequence K
description Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
source Swiss-Prot : SWS_FT_FI3


Display surface

Download
Links