eF-site/Summary 5meq-A

eF-site ID	5meq-A
PDB Code	5meq
Chain	A

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Title	Human Leukocyte Antigen A02 presenting ILAKFLHTL
Classification	IMMUNE SYSTEM
Compound	HLA class I histocompatibility antigen, A-2 alpha chain
Source	Homo sapiens (Human) (5MEQ)

Sequence	A:	GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP

Description

Functional site


1)	chain	A
	residue	97
	type
	sequence	R
	description	binding site for residue EDO C 301
	source	: AC2

2)	chain	A
	residue	147
	type
	sequence	W
	description	binding site for residue EDO C 301
	source	: AC2

3)	chain	A
	residue	152
	type
	sequence	V
	description	binding site for residue EDO C 301
	source	: AC2

4)	chain	A
	residue	257-263
	type	prosite
	sequence	YTCHVQH
	description	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
	source	prosite : PS00290

5)	chain	A
	residue	86
	type	CARBOHYD
	sequence	N
	description	N-linked (GlcNAc...) asparagine => ECO:0000269\|PubMed:19159218
	source	Swiss-Prot : SWS_FT_FI4

6)	chain	A
	residue	73
	type	MOD_RES
	sequence	T
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

7)	chain	A
	residue	84
	type	MOD_RES
	sequence	Y
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

8)	chain	A
	residue	143
	type	MOD_RES
	sequence	T
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

9)	chain	A
	residue	146
	type	MOD_RES
	sequence	K
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

10)	chain	A
	residue	171
	type	MOD_RES
	sequence	Y
	description	Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269\|PubMed:7554280
	source	Swiss-Prot : SWS_FT_FI1

11)	chain	A
	residue	159
	type	CARBOHYD
	sequence	Y
	description	N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269\|PubMed:7918443
	source	Swiss-Prot : SWS_FT_FI2