eF-site ID 5mep-A
PDB Code 5mep
Chain A

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Title Human Leukocyte Antigen A02 presenting ILGKFLHWL
Classification IMMUNE SYSTEM
Compound HLA class I histocompatibility antigen, A-2 alpha chain
Source Homo sapiens (Human) (5MEP)
Sequence A:  GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA
ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT
LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG
KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL
EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT
FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP
Description


Functional site

1) chain A
residue 185
type
sequence P
description binding site for residue EDO A 301
source : AC1

2) chain A
residue 187
type
sequence T
description binding site for residue EDO A 301
source : AC1

3) chain A
residue 8
type
sequence F
description binding site for residue SO4 A 302
source : AC2

4) chain A
residue 29
type
sequence D
description binding site for residue SO4 A 302
source : AC2

5) chain A
residue 30
type
sequence D
description binding site for residue SO4 A 302
source : AC2

6) chain A
residue 234
type
sequence R
description binding site for residue EDO B 101
source : AC3

7) chain A
residue 242
type
sequence Q
description binding site for residue EDO B 101
source : AC3

8) chain A
residue 177
type
sequence E
description binding site for residue EDO D 303
source : AD1

9) chain A
residue 86
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
source Swiss-Prot : SWS_FT_FI4

10) chain A
residue 257-263
type prosite
sequence YTCHVQH
description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
source prosite : PS00290

11) chain A
residue 84
type MOD_RES
sequence Y
description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
source Swiss-Prot : SWS_FT_FI1

12) chain A
residue 143
type MOD_RES
sequence T
description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
source Swiss-Prot : SWS_FT_FI1

13) chain A
residue 146
type MOD_RES
sequence K
description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
source Swiss-Prot : SWS_FT_FI1

14) chain A
residue 171
type MOD_RES
sequence Y
description Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
source Swiss-Prot : SWS_FT_FI1


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