eF-site ID 5m7f-B PDB Code 5m7f Chain B click to enlarge Title Human porphobilinogen deaminase in complex with DPM cofactor Classification TRANSFERASE Compound Porphobilinogen deaminase Source (HEM3_HUMAN) Sequence B:  VIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSLF TKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRE NPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRK FPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMG WHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGV LHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLY LTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVG ITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDV Description Functional site 1) chain B residue 300 type sequence H description binding site for residue SO4 B 402 source : AC5 2) chain B residue 302 type sequence P description binding site for residue SO4 B 402 source : AC5 3) chain B residue 303 type sequence A description binding site for residue SO4 B 402 source : AC5 4) chain B residue 304 type sequence Q description binding site for residue SO4 B 402 source : AC5 5) chain B residue 119 type sequence P description binding site for residue SO4 B 403 source : AC6 6) chain B residue 120 type sequence H description binding site for residue SO4 B 403 source : AC6 7) chain B residue 246 type sequence R description binding site for residue SO4 B 403 source : AC6 8) chain B residue 29 type sequence Q description binding site for residue SO4 B 404 source : AC7 9) chain B residue 169 type sequence N description binding site for residue SO4 B 404 source : AC7 10) chain B residue 96 type sequence S description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 11) chain B residue 98 type sequence K description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 12) chain B residue 99 type sequence D description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 13) chain B residue 145 type sequence T description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 14) chain B residue 146 type sequence S description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 15) chain B residue 147 type sequence S description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 16) chain B residue 149 type sequence R description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 17) chain B residue 150 type sequence R description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 18) chain B residue 173 type sequence R description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 19) chain B residue 188 type sequence L description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 20) chain B residue 189 type sequence A description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 21) chain B residue 195 type sequence R description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 22) chain B residue 217 type sequence Q description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 23) chain B residue 218 type sequence G description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 24) chain B residue 260 type sequence G description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 25) chain B residue 262 type sequence S description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 26) chain B residue 263 type sequence V description binding site for Di-peptide DPM B 401 and CYS B 261 source : AC8 27) chain B residue 278 type MOD_RES sequence L description S-(dipyrrolylmethanemethyl)cysteine => ECO:0000269|PubMed:18936296 source Swiss-Prot : SWS_FT_FI4 28) chain B residue 32 type MOD_RES sequence R description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 29) chain B residue 86 type MOD_RES sequence E description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 164 type MOD_RES sequence R description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 31) chain B residue 91 type MOD_RES sequence D description N6-acetyllysine => ECO:0000250|UniProtKB:P22907 source Swiss-Prot : SWS_FT_FI3

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