eF-site ID 5m6r-A PDB Code 5m6r Chain A click to enlarge Title Human porphobilinogen deaminase in complex with reaction intermediate Classification TRANSFERASE Compound Porphobilinogen deaminase Source (HEM3_HUMAN) Sequence A:  MRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMS TTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSL KDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETL PEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKL DEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQ GALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHL EGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQA TIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGIS LANLLLSKGAKNILDVARQL Description Functional site 1) chain A residue 72 type sequence G description binding site for residue 7J8 A 401 source : AC1 2) chain A residue 73 type sequence E description binding site for residue 7J8 A 401 source : AC1 3) chain A residue 96 type sequence S description binding site for residue 7J8 A 401 source : AC1 4) chain A residue 98 type sequence K description binding site for residue 7J8 A 401 source : AC1 5) chain A residue 99 type sequence D description binding site for residue 7J8 A 401 source : AC1 6) chain A residue 100 type sequence L description binding site for residue 7J8 A 401 source : AC1 7) chain A residue 101 type sequence P description binding site for residue 7J8 A 401 source : AC1 8) chain A residue 102 type sequence T description binding site for residue 7J8 A 401 source : AC1 9) chain A residue 146 type sequence S description binding site for residue 7J8 A 401 source : AC1 10) chain A residue 147 type sequence S description binding site for residue 7J8 A 401 source : AC1 11) chain A residue 149 type sequence R description binding site for residue 7J8 A 401 source : AC1 12) chain A residue 150 type sequence R description binding site for residue 7J8 A 401 source : AC1 13) chain A residue 173 type sequence R description binding site for residue 7J8 A 401 source : AC1 14) chain A residue 189 type sequence A description binding site for residue 7J8 A 401 source : AC1 15) chain A residue 195 type sequence R description binding site for residue 7J8 A 401 source : AC1 16) chain A residue 214 type sequence A description binding site for residue 7J8 A 401 source : AC1 17) chain A residue 215 type sequence V description binding site for residue 7J8 A 401 source : AC1 18) chain A residue 217 type sequence Q description binding site for residue 7J8 A 401 source : AC1 19) chain A residue 218 type sequence G description binding site for residue 7J8 A 401 source : AC1 20) chain A residue 254 type sequence L description binding site for residue 7J8 A 401 source : AC1 21) chain A residue 260 type sequence G description binding site for residue 7J8 A 401 source : AC1 22) chain A residue 261 type sequence C description binding site for residue 7J8 A 401 source : AC1 23) chain A residue 262 type sequence S description binding site for residue 7J8 A 401 source : AC1 24) chain A residue 26 type sequence R description binding site for residue PO4 A 402 source : AC2 25) chain A residue 95 type sequence H description binding site for residue PO4 A 402 source : AC2 26) chain A residue 96 type sequence S description binding site for residue PO4 A 402 source : AC2 27) chain A residue 99 type sequence D description binding site for residue PO4 A 402 source : AC2 28) chain A residue 47 type sequence P description binding site for residue PO4 A 403 source : AC3 29) chain A residue 48 type sequence G description binding site for residue PO4 A 403 source : AC3 30) chain A residue 49 type sequence L description binding site for residue PO4 A 403 source : AC3 31) chain A residue 50 type sequence Q description binding site for residue PO4 A 403 source : AC3 32) chain A residue 120 type sequence H description binding site for residue EPE A 404 source : AC4 33) chain A residue 208 type sequence P description binding site for residue EPE A 404 source : AC4 34) chain A residue 209 type sequence E description binding site for residue EPE A 404 source : AC4 35) chain A residue 268 type sequence H description binding site for residue EPE A 404 source : AC4 36) chain A residue 261 type MOD_RES sequence C description S-(dipyrrolylmethanemethyl)cysteine => ECO:0000269|PubMed:18936296 source Swiss-Prot : SWS_FT_FI4 37) chain A residue 250-266 type prosite sequence ERAFLRHLEGGCSVPVA description PORPHOBILINOGEN_DEAM Porphobilinogen deaminase cofactor-binding site. ERaFlrhLeGGCsVPVA source prosite : PS00533 38) chain A residue 69 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 39) chain A residue 147 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI2 40) chain A residue 74 type MOD_RES sequence K description N6-acetyllysine => ECO:0000250|UniProtKB:P22907 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links