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eF-site ID
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5m3m-I |
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PDB Code
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5m3m |
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Chain
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I |
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click to enlarge
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Title
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Free monomeric RNA polymerase I at 4.0A resolution |
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Classification
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TRANSCRIPTION |
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Compound
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DNA-directed RNA polymerase I subunit RPA190 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); |
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Sequence
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I: |
SVVGSLIFCLDCGDLLENPNAVLGSNVECSQCKAIYPKSQ
FSNLKVVTTTADDAFPSSLRAKKSVVKTSLKKNELKDGAT
IKEKCPQCGNEEMNYHTLATVFYTCTSCGYKFRTNN
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Description
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(1) |
DNA-directed RNA polymerase I subunit RPA190 (E.C.2.7.7.6), DNA-directed RNA polymerase I subunit RPA135 (E.C.2.7.7.6), DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA-directed RNA polymerase I subunit RPA49, DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA14, DNA-directed RNA polymerase I subunit RPA43
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Functional site
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1)
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chain |
I |
| residue |
10 |
| type |
|
| sequence |
C
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| description |
binding site for residue ZN I 3001
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| source |
: AC5
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2)
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chain |
I |
| residue |
11 |
| type |
|
| sequence |
L
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| description |
binding site for residue ZN I 3001
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| source |
: AC5
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3)
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chain |
I |
| residue |
12 |
| type |
|
| sequence |
D
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| description |
binding site for residue ZN I 3001
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| source |
: AC5
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|
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4)
|
chain |
I |
| residue |
13 |
| type |
|
| sequence |
C
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| description |
binding site for residue ZN I 3001
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| source |
: AC5
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|
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5)
|
chain |
I |
| residue |
86 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 3002
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| source |
: AC6
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6)
|
chain |
I |
| residue |
94 |
| type |
|
| sequence |
M
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| description |
binding site for residue ZN I 3002
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| source |
: AC6
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7)
|
chain |
I |
| residue |
114 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 3002
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| source |
: AC6
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|
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8)
|
chain |
I |
| residue |
117 |
| type |
|
| sequence |
C
|
| description |
binding site for residue ZN I 3002
|
| source |
: AC6
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|
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9)
|
chain |
I |
| residue |
119 |
| type |
|
| sequence |
Y
|
| description |
binding site for residue ZN I 3002
|
| source |
: AC6
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10)
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chain |
I |
| residue |
86-121 |
| type |
prosite |
| sequence |
CPQCGNEEMNYHTLATVFYTCTSCGYKF
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| description |
ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpqCgneemnyhtLQLRSaDEGatvfytCts...CgykF
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| source |
prosite : PS00466
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11)
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chain |
I |
| residue |
9-33 |
| type |
prosite |
| sequence |
FCLDCGDLLENPNAVLGSNVECSQC
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| description |
RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FClDCGDLLenpnavlgsnve..CsqC
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| source |
prosite : PS01030
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12)
|
chain |
I |
| residue |
89 |
| type |
MOD_RES |
| sequence |
C
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| description |
Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
|
| source |
Swiss-Prot : SWS_FT_FI3
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13)
|
chain |
I |
| residue |
114 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
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| source |
Swiss-Prot : SWS_FT_FI3
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14)
|
chain |
I |
| residue |
117 |
| type |
MOD_RES |
| sequence |
C
|
| description |
Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
|
| source |
Swiss-Prot : SWS_FT_FI3
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