eF-site ID 5m3m-A PDB Code 5m3m Chain A click to enlarge Title Free monomeric RNA polymerase I at 4.0A resolution Classification TRANSCRIPTION Compound DNA-directed RNA polymerase I subunit RPA190 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence A:  MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDN LGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIE LPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYAC KLRLLQYGLIDESYKLDEITLSSTLLNELKSKRSEYVDMA IAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGK CDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQ DSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLV KADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVL TTSLLIRDLNDDLSKLQKDKVSLEDRRVIFSRLMNAFVTI QNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKH MMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEP VTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMS VEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMN RQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDG DEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLI QDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRS KIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLI SKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASK YGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGM DDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPA DDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSK CVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQ ALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGI KPQEYYFHCMAGREGLIDTAGYLQRCLTKQLEGVHVSYDN SIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYAL LKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQ SVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFK SSDGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEP STQMTLNTFANVTLGIPRLREIVMTASAAIKTPQMTLPIW NDVSDEQADTFCKSISKVLLSEVIDKVIVTETTAARSYVI HMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKE IKKQKKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLE LAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENG KRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGV EAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTY LAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLD SPSARIVVGKLNNVGTGSFDVL Description (1)  DNA-directed RNA polymerase I subunit RPA190 (E.C.2.7.7.6), DNA-directed RNA polymerase I subunit RPA135 (E.C.2.7.7.6), DNA-directed RNA polymerases I and III subunit RPAC1, DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA-directed RNA polymerase I subunit RPA49, DNA-directed RNA polymerase I subunit RPA34, DNA-directed RNA polymerase I subunit RPA14, DNA-directed RNA polymerase I subunit RPA43 Functional site 1) chain A residue 65 type sequence C description binding site for residue ZN A 3001 source : AC1 2) chain A residue 67 type sequence L description binding site for residue ZN A 3001 source : AC1 3) chain A residue 71 type sequence F description binding site for residue ZN A 3001 source : AC1 4) chain A residue 72 type sequence C description binding site for residue ZN A 3001 source : AC1 5) chain A residue 73 type sequence P description binding site for residue ZN A 3001 source : AC1 6) chain A residue 102 type sequence C description binding site for residue ZN A 3002 source : AC2 7) chain A residue 103 type sequence L description binding site for residue ZN A 3002 source : AC2 8) chain A residue 104 type sequence F description binding site for residue ZN A 3002 source : AC2 9) chain A residue 105 type sequence C description binding site for residue ZN A 3002 source : AC2 10) chain A residue 106 type sequence H description binding site for residue ZN A 3002 source : AC2 11) chain A residue 102 type MOD_RES sequence C description Phosphoserine => ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 105 type MOD_RES sequence C description Phosphoserine => ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI1 13) chain A residue 233 type MOD_RES sequence C description Phosphoserine => ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI1 14) chain A residue 236 type MOD_RES sequence C description Phosphoserine => ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI1

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