eF-site ID 5m1p-A
PDB Code 5m1p
Chain A

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Title Crystal structure of the large terminase nuclease from thermophilic phage G20c with bound Calcium
Classification HYDROLASE
Compound Terminase large subunit
Source (5M1P)
Sequence A:  AMNSVFSGLDMLILLPYERRGTRLVVEDYRPDHIYCIGAD
FGKNQDYSVFSVLDLDTGAIACLERMNGATWSDQVARLKA
LSEDYGHAYVVADTWGVGDAIAEELDAQGINYTPLPVKSS
SVKEQLISNLALLMEKGQVAVPNDKTILDELRNFRYYRTA
SGNQVMRAYGRGHDDIVMSLALAYSQY
Description


Functional site

1) chain A
residue 294
type
sequence D
description binding site for residue CA A 501
source : AC1

2) chain A
residue 295
type
sequence F
description binding site for residue CA A 501
source : AC1

3) chain A
residue 300
type
sequence D
description binding site for residue CA A 501
source : AC1

4) chain A
residue 301
type
sequence Y
description binding site for residue CA A 501
source : AC1

5) chain A
residue 429
type
sequence D
description binding site for residue CA A 501
source : AC1

6) chain A
residue 294
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:28100693
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 347
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:28100693
source Swiss-Prot : SWS_FT_FI1

8) chain A
residue 429
type BINDING
sequence D
description BINDING => ECO:0000269|PubMed:28100693
source Swiss-Prot : SWS_FT_FI1

9) chain A
residue 300
type SITE
sequence D
description Modulates nuclease activity => ECO:0000255|HAMAP-Rule:MF_04146
source Swiss-Prot : SWS_FT_FI2

10) chain A
residue 428
type SITE
sequence D
description Possible stabilization of Magnesium 1 => ECO:0000269|PubMed:28100693
source Swiss-Prot : SWS_FT_FI3


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