eF-site ID 5lvp-H
PDB Code 5lvp
Chain H

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Title Human PDK1 Kinase Domain in Complex with an HM-Peptide Bound to the PIF-Pocket
Classification TRANSFERASE
Compound 3-phosphoinositide-dependent protein kinase 1
Source (5LVP)
Sequence H:  FPQFXYS
Description (1)  3-phosphoinositide-dependent protein kinase 1 (E.C.2.7.11.1), hydrophobic-motif peptide of PKB/Akt


Functional site

1) chain H
residue 8
type
sequence F
description binding site for Di-peptide PHE H 11 and SEP H 12
source : AD3

2) chain H
residue 9
type
sequence P
description binding site for Di-peptide PHE H 11 and SEP H 12
source : AD3

3) chain H
residue 10
type
sequence Q
description binding site for Di-peptide PHE H 11 and SEP H 12
source : AD3

4) chain H
residue 13
type
sequence Y
description binding site for Di-peptide PHE H 11 and SEP H 12
source : AD3

5) chain H
residue 10
type
sequence Q
description binding site for Di-peptide SEP H 12 and TYR H 13
source : AD4

6) chain H
residue 11
type
sequence F
description binding site for Di-peptide SEP H 12 and TYR H 13
source : AD4

7) chain H
residue 14
type
sequence S
description binding site for Di-peptide SEP H 12 and TYR H 13
source : AD4


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