eF-site ID 5le7-ABCD PDB Code 5le7 Chain A, B, C, D click to enlarge Title Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_13_D12 Classification DE NOVO PROTEIN Compound DD_D12_13_D12 Source (5LE7) Sequence A:  DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLH LAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGH LEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVL LKNGADVNAQDKFGKTPEDLAKDNGNQWIAQKLEEAKKED LDRKLLEAARAGHRDEVEDLIKNGADVNTADETGFTPLHL AAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHL EIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVLL KHGADVNAQDKFGKTPFDLAIDNGNEDIAEVLQKAA B:  SDLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPL HLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTG HLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEV LLKNGADVNAQDKFGKTPEDLAKDNGNQWIAQKLEEAKKE DLDRKLLEAARAGHRDEVEDLIKNGADVNTADETGFTPLH LAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGH LEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVL LKHGADVNAQDKFGKTPFDLAIDNGNEDIAEVLQKAA C:  GSDLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTP LHLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYT GHLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVE VLLKNGADVNAQDKFGKTPEDLAKDNGNQWIAQKLEEAKK EDLDRKLLEAARAGHRDEVEDLIKNGADVNTADETGFTPL HLAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTG HLEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEV LLKHGADVNAQDKFGKTPFDLAIDNGNEDIAEVLQKAA D:  DLGKKLLEAARAGQDDEVRILLANGADVNTADETGFTPLH LAAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGH LEIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVL LKNGADVNAQDKFGKTPEDLAKDNGNQWIAQKLEEAKKED LDRKLLEAARAGHRDEVEDLIKNGADVNTADETGFTPLHL AAWEGHLGIVEVLLKNGADVNANDERGHTPLHLAAYTGHL EIVEVLLKNGAGVNATDVIGTAPLHLAAMWGHLEIVEVLL KHGADVNAQDKFGKTPFDLAIDNGNEDIAEVLQKAA Description Functional site 1) chain A residue 58 type sequence G description binding site for residue SO4 A 401 source : AC1 2) chain A residue 59 type sequence H description binding site for residue SO4 A 401 source : AC1 3) chain A residue 60 type sequence L description binding site for residue SO4 A 401 source : AC1 4) chain A residue 61 type sequence G description binding site for residue SO4 A 401 source : AC1 5) chain B residue 58 type sequence G description binding site for residue SO4 B 401 source : AC2 6) chain B residue 59 type sequence H description binding site for residue SO4 B 401 source : AC2 7) chain B residue 60 type sequence L description binding site for residue SO4 B 401 source : AC2 8) chain B residue 61 type sequence G description binding site for residue SO4 B 401 source : AC2 9) chain C residue 58 type sequence G description binding site for residue SO4 C 401 source : AC3 10) chain C residue 59 type sequence H description binding site for residue SO4 C 401 source : AC3 11) chain C residue 60 type sequence L description binding site for residue SO4 C 401 source : AC3 12) chain C residue 61 type sequence G description binding site for residue SO4 C 401 source : AC3 13) chain D residue 91 type sequence G description binding site for residue SO4 D 401 source : AC4 14) chain D residue 92 type sequence H description binding site for residue SO4 D 401 source : AC4 15) chain D residue 93 type sequence L description binding site for residue SO4 D 401 source : AC4 16) chain D residue 94 type sequence E description binding site for residue SO4 D 401 source : AC4 17) chain D residue 58 type sequence G description binding site for residue SO4 D 402 source : AC5 18) chain D residue 60 type sequence L description binding site for residue SO4 D 402 source : AC5 19) chain D residue 61 type sequence G description binding site for residue SO4 D 402 source : AC5

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