eF-site ID 5l5x-b PDB Code 5l5x Chain b click to enlarge Title Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with ONX 0914 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence b:  TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL Description Functional site 1) chain b residue 2 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 2) chain b residue 3 type sequence I description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 3) chain b residue 17 type sequence D description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 4) chain b residue 19 type sequence R description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 5) chain b residue 20 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 6) chain b residue 21 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 7) chain b residue 31 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 8) chain b residue 33 type sequence K description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 9) chain b residue 45 type sequence R description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 10) chain b residue 47 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 11) chain b residue 49 type sequence A description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 12) chain b residue 128 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 13) chain b residue 129 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 14) chain b residue 130 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 15) chain b residue 168 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 16) chain b residue 169 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE5 17) chain b residue 2 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 18) chain b residue 3 type sequence I description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 19) chain b residue 17 type sequence D description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 20) chain b residue 19 type sequence R description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 21) chain b residue 20 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 22) chain b residue 21 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 23) chain b residue 31 type sequence T description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 24) chain b residue 33 type sequence K description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 25) chain b residue 45 type sequence R description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 26) chain b residue 47 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 27) chain b residue 49 type sequence A description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 28) chain b residue 128 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 29) chain b residue 129 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 30) chain b residue 130 type sequence G description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 31) chain b residue 168 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 32) chain b residue 169 type sequence S description binding site for Di-peptide 04C b 201 and THR b 1 source : AE6 33) chain b residue 1 type ACT_SITE sequence T description Nucleophile => ECO:0000269|PubMed:9087403 source Swiss-Prot : SWS_FT_FI1 34) chain b residue 4-51 type prosite sequence MAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWC CRSGSAAD description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LAFkFrhGVIVAADsratagayiasqtvk.KvieinpyllgtmaGgaAD source prosite : PS00854

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