eF-site ID 5l5x-J
PDB Code 5l5x
Chain J

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Title Yeast 20S proteasome with human beta5c (1-138) and human beta6 (97-111; 118-133) in complex with ONX 0914
Classification HYDROLASE/HYDROLASE INHIBITOR
Compound Proteasome subunit alpha type-2
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence J:  MDIILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSP
HTLMSFAGEAGDTVQFAEYIQANIQLYSIREDYELSPQAV
SSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQID
YLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDL
LKLCVQELEKRMPMDFKGVIVKIVDKDGIRQVDDF
Description


Functional site

1) chain J
residue 118
type
sequence Q
description binding site for residue MG J 201
source : AC8

2) chain J
residue 124
type
sequence T
description binding site for residue MG J 201
source : AC8

3) chain J
residue 23
type
sequence R
description binding site for residue MES K 303
source : AD2

4) chain J
residue 5-52
type prosite
sequence LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLM
SFAGEAGD
description PROTEASOME_BETA_1 Proteasome beta-type subunits signature. LGIrVqdSVILASSkavtrgisvlkdsdd.KtrqlsphtlmsfaGeaGD
source prosite : PS00854


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