eF-site ID 5l5u-Y PDB Code 5l5u Chain Y click to enlarge Title Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence Y:  TTTLAFKFQHGVIAAVDSRASAGSYISALRMNKVIEINPY LLGTMSGCAADCQYWERLLAKECRLYYLRNGERISVSAAS KLLSNMMCQYRGMGLSMGSMICGWDKKGPGLYYVDEHGTR LSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSI LAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVK EEEGSFNNVIG Description Functional site 1) chain Y residue 19 type sequence R description binding site for residue MG I 302 source : AC6 2) chain Y residue 164 type sequence A description binding site for residue MG I 302 source : AC6 3) chain Y residue 167 type sequence D description binding site for residue MG I 302 source : AC6 4) chain Y residue 170 type sequence S description binding site for residue MG I 302 source : AC6 5) chain Y residue 165 type sequence H description binding site for residue MG Y 301 source : AD5 6) chain Y residue 167 type sequence D description binding site for residue MG Y 301 source : AD5 7) chain Y residue 2 type sequence T description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 8) chain Y residue 3 type sequence T description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 9) chain Y residue 17 type sequence D description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 10) chain Y residue 19 type sequence R description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 11) chain Y residue 20 type sequence A description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 12) chain Y residue 21 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 13) chain Y residue 27 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 14) chain Y residue 31 type sequence M description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 15) chain Y residue 33 type sequence K description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 16) chain Y residue 45 type sequence M description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 17) chain Y residue 47 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 18) chain Y residue 49 type sequence A description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 19) chain Y residue 129 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 20) chain Y residue 130 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 21) chain Y residue 131 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 22) chain Y residue 169 type sequence Y description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 23) chain Y residue 170 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AD9 24) chain Y residue 2 type sequence T description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 25) chain Y residue 3 type sequence T description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 26) chain Y residue 17 type sequence D description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 27) chain Y residue 19 type sequence R description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 28) chain Y residue 20 type sequence A description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 29) chain Y residue 21 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 30) chain Y residue 27 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 31) chain Y residue 31 type sequence M description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 32) chain Y residue 33 type sequence K description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 33) chain Y residue 45 type sequence M description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 34) chain Y residue 47 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 35) chain Y residue 49 type sequence A description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 36) chain Y residue 129 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 37) chain Y residue 130 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 38) chain Y residue 131 type sequence G description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 39) chain Y residue 169 type sequence Y description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1 40) chain Y residue 170 type sequence S description binding site for Di-peptide 04C Y 302 and THR Y 1 source : AE1

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