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Title
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Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome subunit alpha type-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); |
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Sequence
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S: |
NNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTH
AVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARV
LSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSY
GGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGA
RSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRD
ESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI
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Description
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