eF-site ID 5l5u-N PDB Code 5l5u Chain N click to enlarge Title Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence N:  TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL Description Functional site 1) chain N residue 19 type sequence R description binding site for residue MG N 201 source : AD2 2) chain N residue 163 type sequence I description binding site for residue MG N 201 source : AD2 3) chain N residue 166 type sequence D description binding site for residue MG N 201 source : AD2 4) chain N residue 169 type sequence S description binding site for residue MG N 201 source : AD2 5) chain N residue 51 type sequence D description binding site for residue MG N 202 source : AD3 6) chain N residue 92 type sequence N description binding site for residue MG N 202 source : AD3 7) chain N residue 1 type ACT_SITE sequence T description Nucleophile => ECO:0000269|PubMed:9087403 source Swiss-Prot : SWS_FT_FI1

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