eF-site ID 5l5u-W
PDB Code 5l5u
Chain W

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Title Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17
Classification HYDROLASE/HYDROLASE INHIBITOR
Compound Proteasome subunit alpha type-2
Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c);
Sequence W:  SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
Description


Functional site

1) chain W
residue 204
type
sequence D
description binding site for residue MG K 302
source : AC9

2) chain W
residue 124
type
sequence D
description binding site for Di-peptide 04C V 301 and THR V 1
source : AD7

3) chain W
residue 124
type
sequence D
description binding site for Di-peptide 04C V 301 and THR V 1
source : AD8

4) chain W
residue 69
type MOD_RES
sequence K
description Phosphoserine => ECO:0007744|PubMed:18407956
source Swiss-Prot : SWS_FT_FI2


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