eF-site ID 5l5u-V PDB Code 5l5u Chain V click to enlarge Title Yeast 20S proteasome with human beta5i (1-138; V31M) and human beta6 (97-111; 118-133) in complex with epoxyketone inhibitor 17 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence V:  TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ KSYKFPRGTTAVLKESIVNICDIQEE Description Functional site 1) chain V residue 163 type sequence I description binding site for residue MG L 301 source : AD1 2) chain V residue 166 type sequence D description binding site for residue MG L 301 source : AD1 3) chain V residue 169 type sequence S description binding site for residue MG L 301 source : AD1 4) chain V residue 69 type sequence Y description binding site for residue CL U 301 source : AD4 5) chain V residue 2 type sequence T description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 6) chain V residue 17 type sequence D description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 7) chain V residue 20 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 8) chain V residue 21 type sequence T description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 9) chain V residue 31 type sequence C description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 10) chain V residue 33 type sequence K description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 11) chain V residue 45 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 12) chain V residue 46 type sequence A description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 13) chain V residue 47 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 14) chain V residue 49 type sequence A description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 15) chain V residue 128 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 16) chain V residue 129 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 17) chain V residue 130 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 18) chain V residue 168 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 19) chain V residue 169 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD7 20) chain V residue 2 type sequence T description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 21) chain V residue 17 type sequence D description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 22) chain V residue 20 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 23) chain V residue 21 type sequence T description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 24) chain V residue 31 type sequence C description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 25) chain V residue 33 type sequence K description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 26) chain V residue 45 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 27) chain V residue 46 type sequence A description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 28) chain V residue 47 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 29) chain V residue 49 type sequence A description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 30) chain V residue 128 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 31) chain V residue 129 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 32) chain V residue 130 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 33) chain V residue 168 type sequence G description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 34) chain V residue 169 type sequence S description binding site for Di-peptide 04C V 301 and THR V 1 source : AD8 35) chain V residue 1 type catalytic sequence T description 177 source MCSA : MCSA2 36) chain V residue 17 type catalytic sequence D description 177 source MCSA : MCSA2 37) chain V residue 19 type catalytic sequence R description 177 source MCSA : MCSA2 38) chain V residue 33 type catalytic sequence K description 177 source MCSA : MCSA2 39) chain V residue 47 type catalytic sequence G description 177 source MCSA : MCSA2 40) chain V residue 129 type catalytic sequence S description 177 source MCSA : MCSA2 41) chain V residue 166 type catalytic sequence D description 177 source MCSA : MCSA2 42) chain V residue 169 type catalytic sequence S description 177 source MCSA : MCSA2

Display surface Download Links