|
|
eF-site ID
|
5l5h-N |
|
PDB Code
|
5l5h |
|
Chain
|
N |
|
click to enlarge
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Title
|
Yeast 20S proteasome with human beta5i (1-138) and human beta6 (97-111; 118-133) in complex with PR-924 |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
|
Compound
|
Proteasome subunit alpha type-2 |
|
Source
|
null (PSB1_YEAST) |
|
|
Sequence
|
N: |
TSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDK
IWCCRSGSAADTQAIADIVQYHLELYTSQYGTPSTETAAS
VFKELCYENKDNLTAGIIVAGYDDKNKGEVYTIPLGGSVH
KLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLS
QAIKWDGSSGGVIRMVVLTAAGVERLIFYPDEYEQL
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
N |
| residue |
163 |
| type |
|
| sequence |
I
|
| description |
binding site for residue MG N 201
|
| source |
: AC9
|
|
|
2)
|
chain |
N |
| residue |
166 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG N 201
|
| source |
: AC9
|
|
|
3)
|
chain |
N |
| residue |
169 |
| type |
|
| sequence |
S
|
| description |
binding site for residue MG N 201
|
| source |
: AC9
|
|
|
4)
|
chain |
N |
| residue |
51 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG N 202
|
| source |
: AD1
|
|
|
5)
|
chain |
N |
| residue |
1 |
| type |
ACT_SITE |
| sequence |
T
|
| description |
Nucleophile => ECO:0000269|PubMed:9087403
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|