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eF-site ID
|
5l5h-L |
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PDB Code
|
5l5h |
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Chain
|
L |
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click to enlarge
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Title
|
Yeast 20S proteasome with human beta5i (1-138) and human beta6 (97-111; 118-133) in complex with PR-924 |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome subunit alpha type-2 |
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Source
|
null (PSB1_YEAST) |
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Sequence
|
L: |
QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYE
PKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHN
DKKLSINSAARNIQHLLYSRRFFPYYVYNIIAGLDEDGKG
AVYSFDPVGSYQREQCRAGGAAASLIMPFLDNQVNFKNQY
EPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGD
GLEILIVTKDGVRKEFYELKRD
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Description
|
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Functional site
|
|
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1)
|
chain |
L |
| residue |
130 |
| type |
|
| sequence |
S
|
| description |
binding site for residue 39V K 301
|
| source |
: AC6
|
|
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2)
|
chain |
L |
| residue |
132 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue 39V K 301
|
| source |
: AC6
|
|
|
3)
|
chain |
L |
| residue |
222 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG L 301
|
| source |
: AC8
|
|
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4)
|
chain |
L |
| residue |
13-60 |
| type |
prosite |
| sequence |
LGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVM
SANGFAAD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
|
| source |
prosite : PS00854
|
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