eF-site ID 5l0v-A
PDB Code 5l0v
Chain A

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Title human POGLUT1 in complex with 2F-glucose modified EGF(+) and UDP
Classification TRANSFERASE
Compound Protein O-glucosyltransferase 1
Source (5L0V)
Sequence A:  SKWKVFIDQINRSLENYEPCSSQNCSCYHGVIEEDLTPFR
GGISRKMMAEVVRRKLGTHYQITKNRLYRENDCMFPSRCS
GVEHFILEVIGRLPDMEMVINVRDYPQVPKWMEPAIPVFS
FSKTSEYHDIMYPAWTFWEGGPAVWPIYPTGLGRWDLFRE
DLVRSAAQWPWKKKNSTAYFRGSRTSPERDPLILLSRKNP
KLVDAEYTKNQAWKSMKDTLGKPAAKDVHLVDHCKYKYLF
NFRGVAASFRFKHLFLCGSLVFHVGDEWLEFFYPQLKPWV
HYIPVKTDLSNVQELLQFVKANDDVAQEIAERGSQFIRNH
LQMDDITCYWENLLSEYSKFLSYNVTRRKGYDQIIP
Description (1)  Protein O-glucosyltransferase 1 (E.C.2.4.1.-,2.4.2.26), EGF(+)


Functional site
1) chain A
residue 132
type SITE
sequence R
description Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates => ECO:0000269|PubMed:28775322
source Swiss-Prot : SWS_FT_FI3
2) chain A
residue 240
type SITE
sequence Q
description Interaction with the consensus sequence C-X-S-X-[PA]-C in peptide substrates => ECO:0000269|PubMed:28775322
source Swiss-Prot : SWS_FT_FI3
3) chain A
residue 40
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0V
source Swiss-Prot : SWS_FT_FI4
4) chain A
residue 53
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0V
source Swiss-Prot : SWS_FT_FI4
5) chain A
residue 204
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0V
source Swiss-Prot : SWS_FT_FI4
6) chain A
residue 373
type CARBOHYD
sequence N
description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0V
source Swiss-Prot : SWS_FT_FI4
7) chain A
residue 177
type BINDING
sequence Y
description BINDING => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0U
source Swiss-Prot : SWS_FT_FI2
8) chain A
residue 212
type BINDING
sequence S
description BINDING => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0U
source Swiss-Prot : SWS_FT_FI2
9) chain A
residue 218
type BINDING
sequence R
description BINDING => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0U
source Swiss-Prot : SWS_FT_FI2
10) chain A
residue 274
type BINDING
sequence V
description BINDING => ECO:0000269|PubMed:28775322, ECO:0007744|PDB:5L0U
source Swiss-Prot : SWS_FT_FI2
11) chain A
residue 133
type ACT_SITE
sequence D
description Proton donor/acceptor => ECO:0000305|PubMed:28775322
source Swiss-Prot : SWS_FT_FI1

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