eF-site ID 5krs-A PDB Code 5krs Chain A click to enlarge Title HIV-1 Integrase Catalytic Core Domain in Complex with an Allosteric Inhibitor, 3-(1H-pyrrol-1-yl)-2-thiophenecarboxylic acid Classification hydrolase, transferase/inhibitor Compound Integrase Source Human immunodeficiency virus 1 (Q76353_9HIV1) Sequence A:  DSSPGIWQLDXTHLEGKVILVAVHVASGYIEAEVIPAETG QETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAAXWWAG IKQEFGIPYNPGVIESMNKELKKIIGQVRDQAEHLKTAVQ MAVFIHNKKRKGGGYSAGERIVDIIATD Description Functional site 1) chain A residue 131 type sequence W description binding site for residue DMS A 301 source : AC1 2) chain A residue 65 type sequence X description binding site for residue 6XI A 302 source : AC2 3) chain A residue 92 type sequence E description binding site for residue 6XI A 302 source : AC2 4) chain A residue 93 type sequence T description binding site for residue 6XI A 302 source : AC2 5) chain A residue 94 type sequence G description binding site for residue 6XI A 302 source : AC2 6) chain A residue 119 type sequence S description binding site for residue 6XI A 302 source : AC2 7) chain A residue 120 type sequence N description binding site for residue 6XI A 302 source : AC2 8) chain A residue 122 type sequence T description binding site for residue 6XI A 302 source : AC2 9) chain A residue 123 type sequence S description binding site for residue 6XI A 302 source : AC2 10) chain A residue 170 type sequence E description binding site for residue 6XI A 303 source : AC3 11) chain A residue 64 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 12) chain A residue 116 type BINDING sequence D description source Swiss-Prot : SWS_FT_FI1 13) chain A residue 152 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:P04585 source Swiss-Prot : SWS_FT_FI2

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