eF-site ID 5kal-B PDB Code 5kal Chain B click to enlarge Title Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU Classification Transferase/RNA Compound RNA uridylyltransferase 4 Source Trypanosoma brucei (5KAL) Sequence B:  PPSPAVVGRSLVNSFKVDATYRLVLDCVAAVDPLMRLYTF GSTVVYGVHEKGSDVDFVVLNKTDVEDGKGGDAATQVAKG LQADILAKLARVIRQKHLSWNVEEVRRTRVPVVRVKGDFD ITAYRRNGVRNSALLRAYFEQNPPCRWLSMSIKRWSKQTG LNASVIGGSITSYGFNLMVVYYLLQRNHLQFVPPSTIDVS RVEPLPPHLPLEEPADEGLELGTQVLDFLHFFLHEFDSDK QVISLNRPGITTKEELDWTKSAEDFARMNGEKVHYQWCIE DPYELNLNVGRNVTPLKRDFLRRHLEKARDTALLTI Description Functional site 1) chain B residue 52 type sequence F description binding site for residue UTP B 401 source : AC3 2) chain B residue 54 type sequence S description binding site for residue UTP B 401 source : AC3 3) chain B residue 65 type sequence S description binding site for residue UTP B 401 source : AC3 4) chain B residue 66 type sequence D description binding site for residue UTP B 401 source : AC3 5) chain B residue 68 type sequence D description binding site for residue UTP B 401 source : AC3 6) chain B residue 144 type sequence G description binding site for residue UTP B 401 source : AC3 7) chain B residue 147 type sequence N description binding site for residue UTP B 401 source : AC3 8) chain B residue 148 type sequence S description binding site for residue UTP B 401 source : AC3 9) chain B residue 169 type sequence K description binding site for residue UTP B 401 source : AC3 10) chain B residue 173 type sequence K description binding site for residue UTP B 401 source : AC3 11) chain B residue 188 type sequence S description binding site for residue UTP B 401 source : AC3 12) chain B residue 189 type sequence Y description binding site for residue UTP B 401 source : AC3 13) chain B residue 66 type sequence D description binding site for residue MG B 402 source : AC4 14) chain B residue 68 type sequence D description binding site for residue MG B 402 source : AC4 15) chain B residue 66 type sequence D description binding site for residue MG B 403 source : AC5 16) chain B residue 126 type sequence R description binding site for residue MG B 403 source : AC5 17) chain B residue 136 type sequence D description binding site for residue MG B 403 source : AC5 18) chain B residue 169 type BINDING sequence K description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 19) chain B residue 173 type BINDING sequence K description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 20) chain B residue 188 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 21) chain B residue 54 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 22) chain B residue 65 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 23) chain B residue 144 type BINDING sequence G description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI1 24) chain B residue 66 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2NOM, ECO:0007744|PDB:2Q0C, ECO:0007744|PDB:2Q0D, ECO:0007744|PDB:2Q0E, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:2Q0G, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI2 25) chain B residue 68 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17189640, ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2IKF, ECO:0007744|PDB:2NOM, ECO:0007744|PDB:2Q0C, ECO:0007744|PDB:2Q0D, ECO:0007744|PDB:2Q0E, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:2Q0G, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI2 26) chain B residue 121 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17785418, ECO:0000269|PubMed:27744351, ECO:0007744|PDB:2Q0F, ECO:0007744|PDB:2Q0G, ECO:0007744|PDB:5KAL source Swiss-Prot : SWS_FT_FI3 27) chain B residue 136 type SITE sequence D description Important for catalytic activity => ECO:0000269|PubMed:17189640 source Swiss-Prot : SWS_FT_FI4

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