eF-site ID 5k8x-A PDB Code 5k8x Chain A click to enlarge Title Crystal structure of mouse CARM1 in complex with inhibitor U3 Classification TRANSFERASE Compound Histone-arginine methyltransferase CARM1 Source Mus musculus (Mouse) (CARM1_MOUSE) Sequence A:  SVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQR AILQNHTDFKDKIVLDVGCGSGILSFFAAQAGARKIYAVE ASTMAQHAEVLVKSNNLTDRIVVIPGKVEEVSLPEQVDII ISEPMGYMLFNERMLESYLHAKKYLKPSGNMFPTIGDVHL APFTDEQLYMEQFTKANFWYQPSFHGVDLSALRGAAVDEY FRQPVVDTFDIRILMAKSVKYTVNFLEAKEGDLHRIEIPF KFHMLHSGLVHGLAFWFDVAFIGSIMTVWLSTAPTEPLTH WYQVRCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVA QVDQTGSKSSNLLDLKNPFFRYT Description Functional site 1) chain A residue 150 type sequence Y description binding site for residue 6ZH A 501 source : AC1 2) chain A residue 151 type sequence F description binding site for residue 6ZH A 501 source : AC1 3) chain A residue 154 type sequence Y description binding site for residue 6ZH A 501 source : AC1 4) chain A residue 193 type sequence G description binding site for residue 6ZH A 501 source : AC1 5) chain A residue 215 type sequence E description binding site for residue 6ZH A 501 source : AC1 6) chain A residue 216 type sequence A description binding site for residue 6ZH A 501 source : AC1 7) chain A residue 241 type sequence G description binding site for residue 6ZH A 501 source : AC1 8) chain A residue 242 type sequence K description binding site for residue 6ZH A 501 source : AC1 9) chain A residue 243 type sequence V description binding site for residue 6ZH A 501 source : AC1 10) chain A residue 244 type sequence E description binding site for residue 6ZH A 501 source : AC1 11) chain A residue 258 type sequence E description binding site for residue 6ZH A 501 source : AC1 12) chain A residue 260 type sequence M description binding site for residue 6ZH A 501 source : AC1 13) chain A residue 267 type sequence E description binding site for residue 6ZH A 501 source : AC1 14) chain A residue 269 type sequence M description binding site for residue 6ZH A 501 source : AC1 15) chain A residue 272 type sequence S description binding site for residue 6ZH A 501 source : AC1 16) chain A residue 404 type sequence W description binding site for residue EDO A 502 source : AC2 17) chain A residue 413 type sequence L description binding site for residue EDO A 503 source : AC3 18) chain A residue 414 type sequence T description binding site for residue EDO A 503 source : AC3 19) chain A residue 417 type sequence Y description binding site for residue EDO A 503 source : AC3 20) chain A residue 153 type sequence F description binding site for residue EDO A 504 source : AC4 21) chain A residue 159 type sequence Q description binding site for residue EDO A 504 source : AC4 22) chain A residue 144 type sequence E description binding site for residue EDO A 505 source : AC5 23) chain A residue 242 type sequence K description binding site for residue EDO A 505 source : AC5 24) chain A residue 283 type sequence S description binding site for residue PEG A 506 source : AC6 25) chain A residue 398 type sequence G description binding site for residue PEG A 506 source : AC6 26) chain A residue 399 type sequence S description binding site for residue PEG A 506 source : AC6 27) chain A residue 277 type sequence K description binding site for residue PEG A 507 source : AC7 28) chain A residue 280 type sequence L description binding site for residue PEG A 507 source : AC7 29) chain A residue 282 type sequence P description binding site for residue PEG A 507 source : AC7 30) chain A residue 153 type sequence F description binding site for residue PG4 A 508 source : AC8 31) chain A residue 262 type sequence Y description binding site for residue PG4 A 508 source : AC8 32) chain A residue 267 type sequence E description binding site for residue PG4 A 508 source : AC8 33) chain A residue 415 type sequence H description binding site for residue PG4 A 508 source : AC8 34) chain A residue 416 type sequence W description binding site for residue PG4 A 508 source : AC8 35) chain A residue 456 type sequence Q description binding site for residue PE8 A 509 source : AC9 36) chain A residue 463 type sequence K description binding site for residue PE8 A 509 source : AC9 37) chain A residue 160 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 38) chain A residue 169 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 39) chain A residue 193 type BINDING sequence G description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 40) chain A residue 215 type BINDING sequence E description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 41) chain A residue 244 type BINDING sequence E description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 42) chain A residue 272 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17882261 source Swiss-Prot : SWS_FT_FI1 43) chain A residue 217 type MOD_RES sequence S description Phosphoserine => ECO:0000269|PubMed:19843527 source Swiss-Prot : SWS_FT_FI2 44) chain A residue 228 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q86X55 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links