|
eF-site ID
|
5juy-M |
PDB Code
|
5juy |
Chain
|
M |
|
click to enlarge
|
|
Title
|
Active human apoptosome with procaspase-9 |
Classification
|
APOPTOSIS |
Compound
|
Apoptotic protease-activating factor 1 |
Source
|
ORGANISM_COMMON: Bovine; ORGANISM_SCIENTIFIC: Bos taurus; |
|
Sequence
|
M: |
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKT
GQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKM
IFAGIKKKGEREDLIAYLKKATNE
|
|
Description
|
(1) |
Apoptotic protease-activating factor 1, Cytochrome c, Caspase-9 (E.C.3.4.22.62)
|
|
Functional site
|
|
1)
|
chain |
M |
residue |
14 |
type |
BINDING |
sequence |
C
|
description |
covalent
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
2)
|
chain |
M |
residue |
17 |
type |
BINDING |
sequence |
C
|
description |
covalent
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
3)
|
chain |
M |
residue |
18 |
type |
BINDING |
sequence |
H
|
description |
axial binding residue
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
4)
|
chain |
M |
residue |
80 |
type |
BINDING |
sequence |
M
|
description |
axial binding residue
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
5)
|
chain |
M |
residue |
1 |
type |
MOD_RES |
sequence |
G
|
description |
N-acetylglycine => ECO:0000269|PubMed:5933874
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
6)
|
chain |
M |
residue |
48 |
type |
MOD_RES |
sequence |
Y
|
description |
Phosphotyrosine => ECO:0000269|PubMed:16866357
|
source |
Swiss-Prot : SWS_FT_FI4
|
|
7)
|
chain |
M |
residue |
55 |
type |
MOD_RES |
sequence |
K
|
description |
N6-succinyllysine => ECO:0000250|UniProtKB:P62897
|
source |
Swiss-Prot : SWS_FT_FI5
|
|
8)
|
chain |
M |
residue |
72 |
type |
MOD_RES |
sequence |
K
|
description |
N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897
|
source |
Swiss-Prot : SWS_FT_FI6
|
|
9)
|
chain |
M |
residue |
97 |
type |
MOD_RES |
sequence |
Y
|
description |
Phosphotyrosine => ECO:0000269|PubMed:18471988
|
source |
Swiss-Prot : SWS_FT_FI7
|
|
10)
|
chain |
M |
residue |
99 |
type |
MOD_RES |
sequence |
K
|
description |
N6-acetyllysine => ECO:0000250|UniProtKB:P62897
|
source |
Swiss-Prot : SWS_FT_FI8
|
|
|
|