eF-site ID 5juy-K
PDB Code 5juy
Chain K

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Title Active human apoptosome with procaspase-9
Classification APOPTOSIS
Compound Apoptotic protease-activating factor 1
Source ORGANISM_COMMON: Bovine; ORGANISM_SCIENTIFIC: Bos taurus;
Sequence K:  GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKT
GQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKM
IFAGIKKKGEREDLIAYLKKATNE
Description (1)  Apoptotic protease-activating factor 1, Cytochrome c, Caspase-9 (E.C.3.4.22.62)


Functional site

1) chain K
residue 14
type BINDING
sequence C
description covalent
source Swiss-Prot : SWS_FT_FI1

2) chain K
residue 17
type BINDING
sequence C
description covalent
source Swiss-Prot : SWS_FT_FI1

3) chain K
residue 18
type BINDING
sequence H
description axial binding residue
source Swiss-Prot : SWS_FT_FI2

4) chain K
residue 80
type BINDING
sequence M
description axial binding residue
source Swiss-Prot : SWS_FT_FI2

5) chain K
residue 99
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P62897
source Swiss-Prot : SWS_FT_FI8

6) chain K
residue 1
type MOD_RES
sequence G
description N-acetylglycine => ECO:0000269|PubMed:5933874
source Swiss-Prot : SWS_FT_FI3

7) chain K
residue 48
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0000269|PubMed:16866357
source Swiss-Prot : SWS_FT_FI4

8) chain K
residue 55
type MOD_RES
sequence K
description N6-succinyllysine => ECO:0000250|UniProtKB:P62897
source Swiss-Prot : SWS_FT_FI5

9) chain K
residue 72
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897
source Swiss-Prot : SWS_FT_FI6

10) chain K
residue 97
type MOD_RES
sequence Y
description Phosphotyrosine => ECO:0000269|PubMed:18471988
source Swiss-Prot : SWS_FT_FI7


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