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|
eF-site ID
|
5juy-H |
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PDB Code
|
5juy |
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Chain
|
H |
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click to enlarge
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Title
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Active human apoptosome with procaspase-9 |
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Classification
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APOPTOSIS |
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Compound
|
Apoptotic protease-activating factor 1 |
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Source
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ORGANISM_COMMON: Bovine; ORGANISM_SCIENTIFIC: Bos taurus; |
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Sequence
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H: |
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKT
GQAPGFSYTDANKNKGITWGEETLMEYLENPKKYIPGTKM
IFAGIKKKGEREDLIAYLKKATNE
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Description
|
(1) |
Apoptotic protease-activating factor 1, Cytochrome c, Caspase-9 (E.C.3.4.22.62)
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Functional site
|
|
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1)
|
chain |
H |
| residue |
14 |
| type |
BINDING |
| sequence |
C
|
| description |
covalent
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
H |
| residue |
17 |
| type |
BINDING |
| sequence |
C
|
| description |
covalent
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
H |
| residue |
18 |
| type |
BINDING |
| sequence |
H
|
| description |
axial binding residue
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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4)
|
chain |
H |
| residue |
80 |
| type |
BINDING |
| sequence |
M
|
| description |
axial binding residue
|
| source |
Swiss-Prot : SWS_FT_FI2
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|
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5)
|
chain |
H |
| residue |
1 |
| type |
MOD_RES |
| sequence |
G
|
| description |
N-acetylglycine => ECO:0000269|PubMed:5933874
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
H |
| residue |
48 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:16866357
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
7)
|
chain |
H |
| residue |
55 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-succinyllysine => ECO:0000250|UniProtKB:P62897
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
8)
|
chain |
H |
| residue |
72 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P62897
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
9)
|
chain |
H |
| residue |
97 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine => ECO:0000269|PubMed:18471988
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
10)
|
chain |
H |
| residue |
99 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:P62897
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
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