|
|
eF-site ID
|
5ikc-ALMN |
|
PDB Code
|
5ikc |
|
Chain
|
A, L, M, N |
|
click to enlarge
|
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Title
|
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN in complex with FAB |
|
Classification
|
TRANSFERASE |
|
Compound
|
MAb 6H10 light chain |
|
Source
|
(DCX_HUMAN) |
|
|
Sequence
|
A: |
DIVMTQSQKLMSTSVGDRVSITCKASQIVDTAVAWYQQKP
GQSPKPLIYLASNRHTGVPDRFTGSGSGTDFTLTINNVQS
DDLADYFCLQHWNYPLTFGAGTKLELKGADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKT
STSPIVKSFNRNE
|
| L: |
DIVMTQSQKLMSTSVGDRVSITCKASQIVDTAVAWYQQKP
GQSPKPLIYLASNRHTGVPDRFTGSGSGTDFTLTINNVQS
DDLADYFCLQHWNYPLTFGAGTKLELKGADAAPTVSIFPP
SSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHST
SPIVKSFNRNE
|
| M: |
AAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRS
LSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSD
NFFKKVEYT
|
| N: |
AAKKVRFYRNGDRYFKGIVYAVSSDRFRSFDALLADLTRS
LSDNINLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSD
NFFKKVEYTK
|
|
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Description
|
(1) |
Fab light chain, Fab heavy chain, fab light chain, Neuronal migration protein doublecortin
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
192-198 |
| type |
prosite |
| sequence |
YTCEATH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
M |
| residue |
70 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by ABL => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
N |
| residue |
70 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by ABL => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
M |
| residue |
74 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKC => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
M |
| residue |
110 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKC => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
N |
| residue |
74 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKC => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
N |
| residue |
110 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by PKC => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
8)
|
chain |
M |
| residue |
90 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2 => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
9)
|
chain |
N |
| residue |
90 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2 => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
10)
|
chain |
M |
| residue |
115 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2, MARK1 and PKA => ECO:0000250|UniProtKB:Q9ESI7
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
11)
|
chain |
N |
| residue |
115 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine; by CK2, MARK1 and PKA => ECO:0000250|UniProtKB:Q9ESI7
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|