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eF-site ID
|
5ijc-A |
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PDB Code
|
5ijc |
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Chain
|
A |
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click to enlarge
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Title
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The crystal structure of mouse TLR4/MD-2/neoseptin-3 complex |
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Classification
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IMMUNE SYSTEM |
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Compound
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Toll-like receptor 4,Variable lymphocyte receptor B |
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Source
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(LY96_MOUSE) |
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Sequence
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A: |
PCIEVVITYQCMDQKLSKVDDIPSSTKNIDLSFNPLKILK
SYSFSNFSELQWLDLSRCEIETIEDKAWHGLHHLSNLILT
GNPIQSFSPGSFSGLTSLENLVAVETKLASLESFPIGQLI
TLKKLNVAHNFIHSCKLPAYFSNLTNLVHVDLSYNYIQTI
TVNDLQFLRENPQVNLSLDMSLNPIDFIQDQAFQGIKLHE
LTLRGNFNSSNIMKTCLQNLAGLHVHRLILGEFKDERNLE
IFEPSIMEGLCDVTIDEFRLTYTNDFSDDIVKFHCLANVS
AMSLAGVSIKYLEDVPKHFKWQSLSIIRCQLKQFPTLDLP
FLKSLTLTMNKGSISFKKVALPSLSYLDLSRNALSFSGCC
SYSDLGTNSLRHLDLSFNGAIIMSANFMGLEELQHLDFQH
STLKRVTEFSAFLSLEKLLYLDISYTNTKIDFDGIFLGLT
SLNTLKMAGNSFKDNTLSNVFANTTNLTFLDLSKCQLEQI
SWGVFDTLHRLQLLNMSHNNLLFLDSSHYNQLYSLKELAL
DTNQLKSVPDGIFDRLTSLQKIWLHTNPWDCSCPRIDYLS
RWLNKNSQKEQGSAKCSGSGKPVRSIICP
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
224-233 |
| type |
prosite |
| sequence |
GIKLHELTLR
|
| description |
ALDOLASE_KDPG_KHG_1 KDPG and KHG aldolases active site. GIklhELTLR
|
| source |
prosite : PS00159
|
|
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2)
|
chain |
A |
| residue |
172 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
A |
| residue |
204 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
237 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
307 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
492 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
524 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17803912, ECO:0007744|PDB:2Z64
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|