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eF-site ID
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5iek-A |
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PDB Code
|
5iek |
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Chain
|
A |
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click to enlarge
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Title
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Structure of HLA-B*40:02 in complex with the endogenous peptide REFSKEPEL |
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Classification
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IMMUNE SYSTEM |
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Compound
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HLA class I histocompatibility antigen, B-40 alpha chain |
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Source
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(5IEK) |
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Sequence
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A: |
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDA
TSPRKEPRAPWIEQEGPEYWDRETQISKTNTQTYRESLRN
LRGYYNQSEAGSHTLQSMYGCDVGPDGRLLRGHNQYAYDG
KDYIALNEDLRSWTAADTAAQITQRKWEAARVAEQLRAYL
EGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRT
FQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEP
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Description
|
(1) |
HLA class I histocompatibility antigen, B-40 alpha chain, Beta-2-microglobulin, ARG-GLU-PHE-SER-LYS-GLU-PRO-GLU-LEU
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Functional site
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1)
|
chain |
A |
| residue |
84 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
A |
| residue |
143 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
|
chain |
A |
| residue |
146 |
| type |
MOD_RES |
| sequence |
K
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
A |
| residue |
152 |
| type |
MOD_RES |
| sequence |
V
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
159 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
171 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
A |
| residue |
257-263 |
| type |
prosite |
| sequence |
YTCHVQH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
|
| source |
prosite : PS00290
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