eF-site ID 5id3_15-ABCDE PDB Code 5id3 Model 15 Chain A, B, C, D, E click to enlarge Title Solution structure of the pore-forming region of C. elegans Mitochondrial Calcium Uniporter (MCU) Classification TRANSPORT PROTEIN Compound Mitochondrial Calcium Uniporter Source (Q21121_CAEEL) Sequence A:  MAALSVDEYKLSREKKLLLQLENAETLLAPLHDAKRKIEQ EAEAHTDRVAWAGFAASGVQTGLFARLTWWEYSWDIVEPV TYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRR AQKQNFDIEKYNRLVTEVDELRNQLKRLRDPLE B:  MAALSVDEYKLSREKKLLLQLENAETLLAPLHDAKRKIEQ EAEAHTDRVAWAGFAASGVQTGLFARLTWWEYSWDIVEPV TYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRR AQKQNFDIEKYNRLVTEVDELRNQLKRLRDPLE C:  MAALSVDEYKLSREKKLLLQLENAETLLAPLHDAKRKIEQ EAEAHTDRVAWAGFAASGVQTGLFARLTWWEYSWDIVEPV TYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRR AQKQNFDIEKYNRLVTEVDELRNQLKRLRDPLE D:  MAALSVDEYKLSREKKLLLQLENAETLLAPLHDAKRKIEQ EAEAHTDRVAWAGFAASGVQTGLFARLTWWEYSWDIVEPV TYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRR AQKQNFDIEKYNRLVTEVDELRNQLKRLRDPLE E:  MAALSVDEYKLSREKKLLLQLENAETLLAPLHDAKRKIEQ EAEAHTDRVAWAGFAASGVQTGLFARLTWWEYSWDIVEPV TYFATYSTVAATFGYYLYTQQSFEYPSARERVYTKQFYRR AQKQNFDIEKYNRLVTEVDELRNQLKRLRDPLE Description Functional site 1) chain A residue 215-234 type TRANSMEM sequence AWAGFAASGVQTGLFARLTW description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 2) chain E residue 244-260 type TRANSMEM sequence PVTYFATYSTVAATFGY description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 3) chain A residue 244-260 type TRANSMEM sequence PVTYFATYSTVAATFGY description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 4) chain B residue 215-234 type TRANSMEM sequence AWAGFAASGVQTGLFARLTW description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 5) chain B residue 244-260 type TRANSMEM sequence PVTYFATYSTVAATFGY description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 6) chain C residue 215-234 type TRANSMEM sequence AWAGFAASGVQTGLFARLTW description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 7) chain C residue 244-260 type TRANSMEM sequence PVTYFATYSTVAATFGY description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 8) chain D residue 215-234 type TRANSMEM sequence AWAGFAASGVQTGLFARLTW description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 9) chain D residue 244-260 type TRANSMEM sequence PVTYFATYSTVAATFGY description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 10) chain E residue 215-234 type TRANSMEM sequence AWAGFAASGVQTGLFARLTW description Helical => ECO:0000269|PubMed:27135929 source Swiss-Prot : SWS_FT_FI1 11) chain A residue 235-243 type TOPO_DOM sequence WEYSWDIVE description Mitochondrial intermembrane => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI2 12) chain B residue 235-243 type TOPO_DOM sequence WEYSWDIVE description Mitochondrial intermembrane => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI2 13) chain C residue 235-243 type TOPO_DOM sequence WEYSWDIVE description Mitochondrial intermembrane => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI2 14) chain D residue 235-243 type TOPO_DOM sequence WEYSWDIVE description Mitochondrial intermembrane => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI2 15) chain E residue 235-243 type TOPO_DOM sequence WEYSWDIVE description Mitochondrial intermembrane => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI2 16) chain A residue 243 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI3 17) chain B residue 243 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI3 18) chain C residue 243 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI3 19) chain D residue 243 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI3 20) chain E residue 243 type BINDING sequence E description BINDING => ECO:0000250|UniProtKB:Q8NE86 source Swiss-Prot : SWS_FT_FI3

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