|
|
eF-site ID
|
5i63-C |
|
PDB Code
|
5i63 |
|
Chain
|
C |
|
click to enlarge
|
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Title
|
Crystal structure of TEM1 beta-lactamase mutant I263N in the presence of 1.2 MPa xenon |
|
Classification
|
HYDROLASE |
|
Compound
|
Beta-lactamase TEM |
|
Source
|
(BLAT_ECOLX) |
|
|
Sequence
|
C: |
HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEER
FPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEY
SPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP
KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAA
MATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAL
PAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTG
SQATMDERNRQIAEIGASLIKHW
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
221 |
| type |
|
| sequence |
L
|
| description |
binding site for residue XE C 302
|
| source |
: AC5
|
|
|
2)
|
chain |
C |
| residue |
70 |
| type |
catalytic |
| sequence |
S
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
3)
|
chain |
C |
| residue |
73 |
| type |
catalytic |
| sequence |
K
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
4)
|
chain |
C |
| residue |
130 |
| type |
catalytic |
| sequence |
S
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
5)
|
chain |
C |
| residue |
166 |
| type |
catalytic |
| sequence |
E
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
6)
|
chain |
C |
| residue |
234 |
| type |
catalytic |
| sequence |
K
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
7)
|
chain |
C |
| residue |
237 |
| type |
catalytic |
| sequence |
A
|
| description |
2
|
| source |
MCSA : MCSA3
|
|
|
8)
|
chain |
C |
| residue |
70 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Acyl-ester intermediate
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
9)
|
chain |
C |
| residue |
168 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
10)
|
chain |
C |
| residue |
234 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|