eF-site ID 5i63-A PDB Code 5i63 Chain A click to enlarge Title Crystal structure of TEM1 beta-lactamase mutant I263N in the presence of 1.2 MPa xenon Classification HYDROLASE Compound Beta-lactamase TEM Source (BLAT_ECOLX) Sequence A:  HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEER FPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEY SPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAA MATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAL PAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTG SQATMDERNRQIAEIGASLIKHW Description Functional site 1) chain A residue 40 type sequence L description binding site for residue XE A 301 source : AC1 2) chain A residue 265 type sequence T description binding site for residue XE A 301 source : AC1 3) chain A residue 263 type sequence N description binding site for residue XE A 302 source : AC2 4) chain A residue 279 type sequence I description binding site for residue XE A 302 source : AC2 5) chain A residue 282 type sequence I description binding site for residue XE A 302 source : AC2 6) chain A residue 70 type catalytic sequence S description 2 source MCSA : MCSA1 7) chain A residue 73 type catalytic sequence K description 2 source MCSA : MCSA1 8) chain A residue 130 type catalytic sequence S description 2 source MCSA : MCSA1 9) chain A residue 166 type catalytic sequence E description 2 source MCSA : MCSA1 10) chain A residue 234 type catalytic sequence K description 2 source MCSA : MCSA1 11) chain A residue 237 type catalytic sequence A description 2 source MCSA : MCSA1 12) chain A residue 66-81 type prosite sequence FPMMSTFKVLLCGAVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMMSTfKvllCGAVL source prosite : PS00146 13) chain A residue 70 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 14) chain A residue 168 type ACT_SITE sequence E description Proton acceptor source Swiss-Prot : SWS_FT_FI2 15) chain A residue 234 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3

Display surface Download Links