|
eF-site ID
|
5i63-C |
PDB Code
|
5i63 |
Chain
|
C |
|
click to enlarge
|
|
Title
|
Crystal structure of TEM1 beta-lactamase mutant I263N in the presence of 1.2 MPa xenon |
Classification
|
HYDROLASE |
Compound
|
Beta-lactamase TEM |
Source
|
(BLAT_ECOLX) |
|
Sequence
|
C: |
HPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRPEER
FPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEY
SPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGP
KELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTTPAA
MATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSAL
PAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVNYTTG
SQATMDERNRQIAEIGASLIKHW
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
C |
residue |
221 |
type |
|
sequence |
L
|
description |
binding site for residue XE C 302
|
source |
: AC5
|
|
2)
|
chain |
C |
residue |
70 |
type |
catalytic |
sequence |
S
|
description |
2
|
source |
MCSA : MCSA3
|
|
3)
|
chain |
C |
residue |
73 |
type |
catalytic |
sequence |
K
|
description |
2
|
source |
MCSA : MCSA3
|
|
4)
|
chain |
C |
residue |
130 |
type |
catalytic |
sequence |
S
|
description |
2
|
source |
MCSA : MCSA3
|
|
5)
|
chain |
C |
residue |
166 |
type |
catalytic |
sequence |
E
|
description |
2
|
source |
MCSA : MCSA3
|
|
6)
|
chain |
C |
residue |
234 |
type |
catalytic |
sequence |
K
|
description |
2
|
source |
MCSA : MCSA3
|
|
7)
|
chain |
C |
residue |
237 |
type |
catalytic |
sequence |
A
|
description |
2
|
source |
MCSA : MCSA3
|
|
8)
|
chain |
C |
residue |
70 |
type |
ACT_SITE |
sequence |
S
|
description |
Acyl-ester intermediate
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
9)
|
chain |
C |
residue |
168 |
type |
ACT_SITE |
sequence |
E
|
description |
Proton acceptor
|
source |
Swiss-Prot : SWS_FT_FI2
|
|
10)
|
chain |
C |
residue |
234 |
type |
BINDING |
sequence |
K
|
description |
|
source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|