|
|
eF-site ID
|
5i3f-A |
|
PDB Code
|
5i3f |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
Structure-Function Studies on Role of Hydrophobic Clamping of a Basic Glutamate in Catalysis by Triosephosphate Isomerase |
|
Classification
|
ISOMERASE |
|
Compound
|
Triosephosphate isomerase, glycosomal |
|
Source
|
Trypanosoma brucei brucei (TPIS_TRYBB) |
|
|
Sequence
|
A: |
SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVV
ASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLP
ILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF
MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAK
VVIAYEPVWAAGTGKVATPQQAQEAHALIRSWVSSKIGAD
VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE
FVDIIKATQ
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
95 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
A |
| residue |
167 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
A |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
A |
| residue |
13 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|