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eF-site ID
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5hbj-B |
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PDB Code
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5hbj |
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Chain
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B |
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click to enlarge
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Title
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CDK8-CYCC IN COMPLEX WITH 8-[2-Amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)-pyridin-4-yl]-2,8-diaza-spiro[4.5]decan-1-one |
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Classification
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TRANSFERASE |
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Compound
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Cyclin-dependent kinase 8 |
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Source
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Homo sapiens (Human) (CCNC_HUMAN) |
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Sequence
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B: |
DKAMAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEY
WKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYS
LKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAAATSVLK
TRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYR
PLLQYVQDMGQEDMLLPLAWRIVNDTYRTDLCLLYPPFMI
ALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKL
YEQWKNFDERKEMATILSKMPKPKPPP
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Description
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(1) |
Cyclin-dependent kinase 8 (E.C.2.7.11.22,2.7.11.23), Cyclin-C
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Functional site
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1)
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chain |
B |
| residue |
41 |
| type |
|
| sequence |
Q
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| description |
binding site for residue FMT B 301
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| source |
: AC3
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