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eF-site ID
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5h43-ABC |
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PDB Code
|
5h43 |
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Chain
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A, B, C |
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click to enlarge
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Title
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Structural and mechanistical studies of the nuclear import by Importin-alpha |
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Classification
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PROTEIN TRANSPORT/TRANSFERASE |
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Compound
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Importin subunit alpha-1 |
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Source
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null (KAT8_HUMAN) |
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Sequence
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A: |
NQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQ
PPIDNIIRAGLIPKFVSFLGRTDCSPIQFESAWALTNIAS
GTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNI
AGDGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNL
TWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLA
DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI
VTPALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKT
NIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA
DFKTQKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNLL
TAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGG
LDKIEALQNHENESVYKASLSLIEKYFS
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| B: |
RNQKRKHDEI
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| C: |
SELAEQPERKITRNQ
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
490 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
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| source |
Swiss-Prot : SWS_FT_FI1
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