eF-site ID 5gwi-CDEF PDB Code 5gwi Chain C, D, E, F click to enlarge Title Structure of a Human topoisomerase IIbeta fragment in complex with DNA and E7873R Classification ISOMERASE/DNA/ISOMERASE INHIBITOR Compound DNA topoisomerase 2-beta Source null (5GWI) Sequence C:  AGCCGAGC D:  TGCAGCTCGGCT E:  AGCCGAGC F:  TGCAGCTCGGCT Description Functional site 1) chain C residue 8 type sequence C description binding site for residue N2R A 1301 source : AC1 2) chain D residue 9 type sequence T description binding site for residue N2R A 1301 source : AC1 3) chain D residue 10 type sequence G description binding site for residue N2R A 1301 source : AC1 4) chain F residue 12 type sequence A description binding site for residue N2R A 1301 source : AC1 5) chain F residue 13 type sequence G description binding site for residue N2R A 1301 source : AC1 6) chain C residue 8 type sequence C description binding site for residue N2N A 1302 source : AC2 7) chain D residue 9 type sequence T description binding site for residue N2N A 1302 source : AC2 8) chain D residue 10 type sequence G description binding site for residue N2N A 1302 source : AC2 9) chain F residue 12 type sequence A description binding site for residue N2N A 1302 source : AC2 10) chain F residue 13 type sequence G description binding site for residue N2N A 1302 source : AC2 11) chain D residue 12 type sequence A description binding site for residue N2R B 1301 source : AC5 12) chain D residue 13 type sequence G description binding site for residue N2R B 1301 source : AC5 13) chain E residue 8 type sequence C description binding site for residue N2R B 1301 source : AC5 14) chain F residue 9 type sequence T description binding site for residue N2R B 1301 source : AC5 15) chain F residue 10 type sequence G description binding site for residue N2R B 1301 source : AC5 16) chain D residue 12 type sequence A description binding site for residue N2N B 1302 source : AC7 17) chain D residue 13 type sequence G description binding site for residue N2N B 1302 source : AC7 18) chain E residue 8 type sequence C description binding site for residue N2N B 1302 source : AC7 19) chain F residue 9 type sequence T description binding site for residue N2N B 1302 source : AC7 20) chain F residue 10 type sequence G description binding site for residue N2N B 1302 source : AC7 21) chain E residue 5 type sequence G description binding site for residue MG E 101 source : AC9

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