eF-site ID 5gtj-ABCD PDB Code 5gtj Chain A, B, C, D click to enlarge Title CRYSTAL STRUCTURE OF CATALYTICALLY ACTIVE FORM OF HUMAN DUSP26 Classification HYDROLASE Compound Dual specificity protein phosphatase 26 Source Homo sapiens (Human) (DUS26_HUMAN) Sequence A:  FLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRR ELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDS PAFDMSIHFQTAADFIHRALSQPGGKILVHSAVGVSRSAT LVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLAL DRRLRQ B:  PFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNR RELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHD SPAFDMSIHFQTAADFIHRALSQPGGKILVHSAVGVSRSA TLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLA LDRRLRQG C:  FLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANNRR ELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAHDS PAFDMSIHFQTAADFIHRALSQPGGKILVHSAVGVSRSAT LVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLLAL DRRLRQ D:  HPFLNVFELERLLYTGKTACNHADEVWPGLYLGDQDMANN RRELRRLGITHVLNASHSRWRGTPEAYEGLGIRYLGVEAH DSPAFDMSIHFQTAADFIHRALSQPGGKILVHSAVGVSRS ATLVLAYLMLYHHLTLVEAIKKVKDHRGIIPNRGFLRQLL ALDRRLRQ Description (1)  Dual specificity protein phosphatase 26 (E.C.3.1.3.16,3.1.3.48) Functional site 1) chain A residue 120 type sequence D description binding site for residue PO4 A 301 source : AC1 2) chain A residue 152 type sequence S description binding site for residue PO4 A 301 source : AC1 3) chain A residue 153 type sequence A description binding site for residue PO4 A 301 source : AC1 4) chain A residue 154 type sequence V description binding site for residue PO4 A 301 source : AC1 5) chain A residue 155 type sequence G description binding site for residue PO4 A 301 source : AC1 6) chain A residue 156 type sequence V description binding site for residue PO4 A 301 source : AC1 7) chain A residue 157 type sequence S description binding site for residue PO4 A 301 source : AC1 8) chain A residue 158 type sequence R description binding site for residue PO4 A 301 source : AC1 9) chain B residue 120 type sequence D description binding site for residue PO4 B 301 source : AC2 10) chain B residue 152 type sequence S description binding site for residue PO4 B 301 source : AC2 11) chain B residue 153 type sequence A description binding site for residue PO4 B 301 source : AC2 12) chain B residue 154 type sequence V description binding site for residue PO4 B 301 source : AC2 13) chain B residue 155 type sequence G description binding site for residue PO4 B 301 source : AC2 14) chain B residue 156 type sequence V description binding site for residue PO4 B 301 source : AC2 15) chain B residue 157 type sequence S description binding site for residue PO4 B 301 source : AC2 16) chain B residue 158 type sequence R description binding site for residue PO4 B 301 source : AC2 17) chain C residue 120 type sequence D description binding site for residue PO4 C 301 source : AC3 18) chain C residue 152 type sequence S description binding site for residue PO4 C 301 source : AC3 19) chain C residue 153 type sequence A description binding site for residue PO4 C 301 source : AC3 20) chain C residue 154 type sequence V description binding site for residue PO4 C 301 source : AC3 21) chain C residue 155 type sequence G description binding site for residue PO4 C 301 source : AC3 22) chain C residue 156 type sequence V description binding site for residue PO4 C 301 source : AC3 23) chain C residue 157 type sequence S description binding site for residue PO4 C 301 source : AC3 24) chain C residue 158 type sequence R description binding site for residue PO4 C 301 source : AC3 25) chain D residue 120 type sequence D description binding site for residue PO4 D 301 source : AC4 26) chain D residue 152 type sequence S description binding site for residue PO4 D 301 source : AC4 27) chain D residue 153 type sequence A description binding site for residue PO4 D 301 source : AC4 28) chain D residue 154 type sequence V description binding site for residue PO4 D 301 source : AC4 29) chain D residue 155 type sequence G description binding site for residue PO4 D 301 source : AC4 30) chain D residue 156 type sequence V description binding site for residue PO4 D 301 source : AC4 31) chain D residue 157 type sequence S description binding site for residue PO4 D 301 source : AC4 32) chain D residue 158 type sequence R description binding site for residue PO4 D 301 source : AC4 33) chain A residue 152 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 source Swiss-Prot : SWS_FT_FI1 34) chain B residue 152 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 source Swiss-Prot : SWS_FT_FI1 35) chain C residue 152 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 source Swiss-Prot : SWS_FT_FI1 36) chain D residue 152 type ACT_SITE sequence S description Phosphocysteine intermediate => ECO:0000255|PROSITE-ProRule:PRU00160 source Swiss-Prot : SWS_FT_FI1

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