eF-site ID 5frx-AB PDB Code 5frx Chain A, B click to enlarge Title crystal structure of the phenol-responsive sensory domain of the transcription activator PoxR in complex with 4-nitrophenol Classification TRANSCRIPTION Compound POSITIVE PHENOL-DEGRADATIVE GENE REGULATOR Source (O84957_9RALS) Sequence A:  RDGLSNLARRLRFAMKEGSIWLGEQRMILLHTAALGALRK ELVDTLGMERARGLFMRMGFHSGVRDAELAKTMRSGHSDF GMLEMGPCLHTIEGVVRVTPLTVDINIAAGVYHGEFLWED SFEGDVHRQMFGVAQAPVCWMQIGYATGYTSALMGKTILY RELECVGCGHPHCRILGKPLEQWEDGEAELALYQPD B:  RDGLSNLARRLRFAMKEGSIWLGEQRMILLHTAALGALRK ELVDTLGMERARGLFMRMGFHSGVRDAELAKTMRSGHSDF GMLEMGPCLHTIEGVVRVTPLTVDINIAAGVYHGEFLWED SFEGDVHRQMFGVAQAPVCWMQIGYATGYTSALMGKTILY RELECVGCGHPHCRILGKPLEQWEDGEAELALYQPD Description (1)  POSITIVE PHENOL-DEGRADATIVE GENE REGULATOR Functional site 1) chain A residue 151 type sequence C description BINDING SITE FOR RESIDUE ZN A 1209 source : AC1 2) chain A residue 174 type sequence E description BINDING SITE FOR RESIDUE ZN A 1209 source : AC1 3) chain A residue 177 type sequence C description BINDING SITE FOR RESIDUE ZN A 1209 source : AC1 4) chain A residue 185 type sequence C description BINDING SITE FOR RESIDUE ZN A 1209 source : AC1 5) chain A residue 95 type sequence L description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 6) chain A residue 98 type sequence G description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 7) chain A residue 99 type sequence P description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 8) chain A residue 102 type sequence H description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 9) chain A residue 110 type sequence V description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 10) chain A residue 124 type sequence Y description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 11) chain A residue 128 type sequence F description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 12) chain A residue 130 type sequence W description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 13) chain A residue 161 type sequence Y description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 14) chain A residue 162 type sequence T description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 15) chain A residue 172 type sequence Y description BINDING SITE FOR RESIDUE NPO A 1210 source : AC2 16) chain B residue 151 type sequence C description BINDING SITE FOR RESIDUE ZN B 1209 source : AC3 17) chain B residue 174 type sequence E description BINDING SITE FOR RESIDUE ZN B 1209 source : AC3 18) chain B residue 177 type sequence C description BINDING SITE FOR RESIDUE ZN B 1209 source : AC3 19) chain B residue 185 type sequence C description BINDING SITE FOR RESIDUE ZN B 1209 source : AC3 20) chain B residue 98 type sequence G description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 21) chain B residue 99 type sequence P description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 22) chain B residue 102 type sequence H description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 23) chain B residue 110 type sequence V description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 24) chain B residue 124 type sequence Y description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 25) chain B residue 128 type sequence F description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 26) chain B residue 130 type sequence W description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 27) chain B residue 161 type sequence Y description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 28) chain B residue 162 type sequence T description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4 29) chain B residue 172 type sequence Y description BINDING SITE FOR RESIDUE NPO B 1210 source : AC4

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