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eF-site ID
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5fob-A |
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PDB Code
|
5fob |
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Chain
|
A |
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click to enlarge
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Title
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Crystal Structure of Human Complement C3b in complex with Smallpox Inhibitor of Complement (SPICE) |
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Classification
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LIPID BINDING PROTEIN |
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Compound
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COMPLEMENT C3 BETA CHAIN |
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Source
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ORGANISM_COMMON: HUMAN; ORGANISM_SCIENTIFIC: HOMO SAPIENS; |
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Sequence
|
A: |
SPMYSIITPNILRLESEETMVLEAHDAQGDVPVTVTVHDF
PGKKLVLSSEKTVLTPATNHMGNVTFTIPANREFKSEKGR
NKFVTVQATFGTQVVEKVVLVSLQSGYLFIQTDKTIYTPG
STVLYRIFTVNHKLLPVGRTVMVNIENPEGIPVKQDSLSS
QNQLGVLPLSWDIPELVNMGQWKIRAYYENSPQQVFSTEF
EVKEYVLPSFEVIVEPTEKFYYIYNEKGLEVTITARFLYG
KKVEGTAFVIFGIQDGEQRISLPESLKRIPIEDGSGEVVL
SRKVLLDGVQNPRAEDLVGKSLYVSATVILHSGSDMVQAE
RSGIPIVTSPYQIHFTKTPKYFKPGMPFDLMVFVTNPDGS
PAYRVPVAVQGEDTVQSLTQGDGVAKLSINTHPSQKPLSI
TVRTKKQELSEAEQATRTMQALPYSTVGNSNNYLHLSVLR
TELRPGETLNVNFLLRMDRAHEAKIRYYTYLIMNKGRLLK
AGRQVREPGQDLVVLPLSITTDFIPSFRLVAYYTLIGASG
QREVVADSVWVDVKDSCVGSLVVKSGQSEDRQPVPGQQMT
LKIEGDHGARVVLVAVDKGVFVLNKKNKLTQSKIWDVVEK
ADIGCTPGSGKDYAGVFSDAGLTFTSSSGQQTAQRAELQC
PQ
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
297 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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2)
|
chain |
A |
| residue |
303 |
| type |
SITE |
| sequence |
S
|
| description |
Cleavage; by factor I
|
| source |
Swiss-Prot : SWS_FT_FI2
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