eF-site ID 5flm-I PDB Code 5flm Chain I click to enlarge Title Structure of transcribing mammalian RNA polymerase II Classification TRANSCRIPTION Compound DNA-DIRECTED RNA POLYMERASE Source ORGANISM_COMMON: BOVINE; ORGANISM_SCIENTIFIC: BOS TAURUS; Sequence I:  VGIRFCQECNNMLYPKEDKENRILLYACRNCDYQQEADNS CIYVNKITHEVDELTQIIADVSQDPTLPRTEDHPCQKCGH KEAVFFQSHSARAEDAMRLYYVCTAPHCGHRWTE Description (1)  DNA-DIRECTED RNA POLYMERASE (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 (E.C.2.7.7.6), DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 Functional site 1) chain I residue 17 type sequence C description BINDING SITE FOR RESIDUE ZN I 1126 source : AC6 2) chain I residue 20 type sequence C description BINDING SITE FOR RESIDUE ZN I 1126 source : AC6 3) chain I residue 39 type sequence C description BINDING SITE FOR RESIDUE ZN I 1126 source : AC6 4) chain I residue 42 type sequence C description BINDING SITE FOR RESIDUE ZN I 1126 source : AC6 5) chain I residue 86 type sequence C description BINDING SITE FOR RESIDUE ZN I 1127 source : AC7 6) chain I residue 89 type sequence C description BINDING SITE FOR RESIDUE ZN I 1127 source : AC7 7) chain I residue 114 type sequence C description BINDING SITE FOR RESIDUE ZN I 1127 source : AC7 8) chain I residue 119 type sequence C description BINDING SITE FOR RESIDUE ZN I 1127 source : AC7 9) chain I residue 112-118 type prosite sequence YVCTAPH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCTAPH source prosite : PS00290 10) chain I residue 86-123 type prosite sequence CQKCGHKEAVFFQSHSARAEDAMRLYYVCTAPHCGHRW description ZF_TFIIS_1 Zinc finger TFIIS-type signature. CqkCghkeavffqSHSARaEDAmrlyyvCtaph.CghrW source prosite : PS00466 11) chain I residue 16-42 type prosite sequence FCQECNNMLYPKEDKENRILLYACRNC description RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCqECNNMLypkedkenrillyaCrnC source prosite : PS01030 12) chain I residue 119 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:P24928 source Swiss-Prot : SWS_FT_FI4 13) chain I residue 20 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28892040, ECO:0007744|PDB:5OIK source Swiss-Prot : SWS_FT_FI3 14) chain I residue 39 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28892040, ECO:0007744|PDB:5OIK source Swiss-Prot : SWS_FT_FI3 15) chain I residue 42 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28892040, ECO:0007744|PDB:5OIK source Swiss-Prot : SWS_FT_FI3

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