eF-site ID 5fiv-A PDB Code 5fiv Chain A click to enlarge Title STRUCTURAL STUDIES OF HIV AND FIV PROTEASES COMPLEXED WITH AN EFFICIENT INHIBITOR OF FIV PR Classification HYDROLASE/HYDROLASE INHIBITOR Compound RETROPEPSIN Source Feline immunodeficiency virus (isolate Petaluma) (FIV) (POL_FIVPE) Sequence A:  GTTTTLEKRPEILIFVNGYPIKFLLDTGADITILNRRDFQ VKNSIENGRQNMIGIGGGKRGTNYINVHLEIRDENYKTQC IFGNVCVLEDNSLIQPLLGRDNMIKFNIRLVM Description Functional site 1) chain A residue 24 type sequence P description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 2) chain A residue 30 type sequence D description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 3) chain A residue 30 type sequence D description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 4) chain A residue 32 type sequence G description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 5) chain A residue 33 type sequence A description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 6) chain A residue 34 type sequence D description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 7) chain A residue 37 type sequence I description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 8) chain A residue 55 type sequence N description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 9) chain A residue 56 type sequence M description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 10) chain A residue 57 type sequence I description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 11) chain A residue 58 type sequence G description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 12) chain A residue 59 type sequence I description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 13) chain A residue 101 type sequence L description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 14) chain A residue 101 type sequence L description BINDING SITE FOR RESIDUE 3TL A 201 source : AC1 15) chain A residue 27-38 type prosite sequence FLLDTGADITIL description ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FLLDTGADITIL source prosite : PS00141 16) chain A residue 30 type ACT_SITE sequence D description For protease activity source Swiss-Prot : SWS_FT_FI1

Display surface Download Links