eF-site ID 5fg4-A PDB Code 5fg4 Chain A click to enlarge Title Crystal structure of the bromodomain of human BRPF1 in complex with OF-1 chemical probe Classification TRANSCRIPTION Compound Peregrin Source Homo sapiens (Human) (BRPF1_HUMAN) Sequence A:  MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLD HIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLKY NAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG Description Functional site 1) chain A residue 639 type sequence K description binding site for residue 5XE A 801 source : AC1 2) chain A residue 652 type sequence I description binding site for residue 5XE A 801 source : AC1 3) chain A residue 653 type sequence F description binding site for residue 5XE A 801 source : AC1 4) chain A residue 657 type sequence V description binding site for residue 5XE A 801 source : AC1 5) chain A residue 658 type sequence P description binding site for residue 5XE A 801 source : AC1 6) chain A residue 661 type sequence E description binding site for residue 5XE A 801 source : AC1 7) chain A residue 662 type sequence V description binding site for residue 5XE A 801 source : AC1 8) chain A residue 708 type sequence N description binding site for residue 5XE A 801 source : AC1 9) chain A residue 714 type sequence F description binding site for residue 5XE A 801 source : AC1 10) chain A residue 650-707 type prosite sequence GNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLN FDDFEEDFNLIVSNCLKY description BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY source prosite : PS00633

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